Methotrexate Impurity 62 CAS 942840-87-1
| CAS No. | 942840-87-1 |
| Molecular Formula | C9H12N2O |
| Molecular Weight | 164.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Methotrexate Impurity 62 (CAS 942840-87-1) is a certified pharmaceutical impurity reference standard with the molecular formula C9H12N2O and a molecular weight of 164.20 g/mol.
The molecular framework of Methotrexate Impurity 62 (C9H12N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Methotrexate Impurity 62 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12N2O |
| Molecular Weight | 164.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methotrexate Standards
- Methotrexate Impurity 25 (CAS CATO-C4X-115425)
- Methotrexate Impurity 26 (CAS CATO-C4X-115426)
- Methotrexate Impurity N2 (CAS 708-74-7)
- Methotrexate impurity N1 (CAS 4215-07-0)
- Methotrexate Impurity N6 (CAS 4261-17-0)
- Methotrexate Impurity 27 (CAS 64620-79-7)
- Methotrexate EP Impurity A (CAS 945-24-4)
- Methotrexate Impurity 30 (CAS 881-33-4)
Recommended Standards
- Benidipine Impurity 55 (CAS CATO-C4X-112055)
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- Posaconazole Impurity 118 (CAS 81445-45-6)
- Telmisartan EP Impurity E (CAS 884330-12-5)
- Oseltamivir Impurity 2HCI 131 (CAS CATO-C4X-1720131)
- Bumetanide Impurity 117 (CAS 74917-54-7)
- 1-(4-Methoxybutyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1429902-32-8)
- 1-(4-methyl-2-pyridinyl)ethanone 1-(4-methylpyridin-2-yl)ethanone 59576-26-0 A832370 (CAS 59576-26-0)
- (1S,2S,3R,4R)-Peramivir Impurity 95 (CAS 229615-05-8)
- 6-Amino-5-nitropyrimidin-4-ol (CAS 36746-26-6)
- Apioside (CAS 26544-34-3)
- (R)-2-(5-Chloro-2-methoxyphenyl)piperidine (CAS 1213631-49-2)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com