Levofloxacin Impurity 44 CAS 94714-58-6
| CAS No. | 94714-58-6 |
| Molecular Formula | C14H12F4O4 |
| Molecular Weight | 320.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Levofloxacin Impurity 44 (C14H12F4O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Levofloxacin Impurity 44 (CAS 94714-58-6, C14H12F4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Levofloxacin Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12F4O4 |
| Molecular Weight | 320.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Levofloxacin Standards
- Levofloxacin impurity 01 (CAS 154228-18-9)
- Levofloxacin Impurity 94 (CAS CATO-C4X-137194)
- Levofloxacin Impurity 21 (CAS 1797510-34-9)
- Levofloxacin Impurity 100 (CAS 104600-15-9)
- Levofloxacin Descarboxy Impurity（Levofloxacin EP Impurity E） (CAS 178964-53-9)
- Levofloxacin Impurity 17 (CAS CATO-C4X-137117)
- Levofloxacin impurity 66 (CAS CATO-C4X-137166)
- Levofloxacin Impurity 82 (CAS 110548-03-3)
Recommended Standards
- Ethyl 7-nitro-5-(trifluoromethyl)benzo[d]thiazole-2-carboxylate (CAS 40160-42-7)
- 6-[4-(difluoromethoxy)phenyl]-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1011398-65-4)
- Ethyl 5-nitro-7-(trifluoromethyl)benzo[d]thiazole-2-carboxylate (CAS 40160-45-0)
- 7-(Difluoromethyl)-5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 1018053-78-5)
- Tadalafil Impurity 116 (CAS CATO-C4X-1087116)
- Estradiol Impurity 51 (CAS 165609-57-4)
- Afoxolaner impurity 4 (CAS CATO-C4X-31374)
- 3-Bromo-2-chloro-5-fluorophenol (CAS 1805479-20-2)
- 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine (CAS 2223035-26-3)
- 2-Bromobenzyl carbonochloridate (CAS 80070-89-9)
- N1,N1,N1,N6,N6,N6-Hexaethylhexane-1,6-diaminium bromide (CAS 7072-43-7)
- 1-tert-butoxycarbonyl-3-hydroxy-azetidine-2-carboxylic acid (CAS 1822531-69-0)
- 2-(3-Fluoro-4-methoxybenzyl)piperidine hydrochloride (CAS 1170364-71-2)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com