Levofloxacin impurity 66 CAS CATO-C4X-137166
| CAS No. | CATO-C4X-137166 |
| Molecular Formula | C16H17N3O4 |
| Molecular Weight | 315.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Levofloxacin impurity 66 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Levofloxacin impurity 66 (CAS CATO-C4X-137166), a pharmacopoeial impurity reference standard (molecular formula C16H17N3O4, MW 315.32 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Levofloxacin impurity 66 (C16H17N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Levofloxacin impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H17N3O4 |
| Molecular Weight | 315.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Levofloxacin Standards
- Levofloxacin Impurity 17 (CAS CATO-C4X-137117)
- Levofloxacin Descarboxy Impurity（Levofloxacin EP Impurity E） (CAS 178964-53-9)
- Levofloxacin Impurity 100 (CAS 104600-15-9)
- Levofloxacin impurity 01 (CAS 154228-18-9)
- Levofloxacin Impurity 94 (CAS CATO-C4X-137194)
- Levofloxacin Impurity 44 (CAS 94714-58-6)
- Levofloxacin Impurity 21 (CAS 1797510-34-9)
- Levofloxacin Impurity 26 (CAS 106939-34-8)
Recommended Standards
- Naltrexone EP Impurity A (CAS 1007856-83-8)
- Sorafenib Impurity 2(PAPE-ethyl carbamate) (CAS 2206827-12-3)
- Pranoprofen Impurity 24 (CAS CATO-C4X-181124)
- Mirabegron Impurity 91 (CAS 3032026-53-9)
- Aprocitentan Impurity 5 (CAS CATO-C4X-33555)
- Miconazole EP Impurity D (CAS 24168-96-5)
- Amlodipine Impurity 92 formate (CAS 2923811-73-6(free base))
- Ethyl 4-ethoxy-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carboxylate (CAS 886951-78-6)
- [(2,4-difluorophenyl)methyl](ethyl)amine (CAS 1016859-58-7)
- 1-(3-(Bromomethyl)phenyl)-1H-1,2,4-triazole hydrobromide (CAS 1956341-43-7)
- Ac-Lys-AMC (CAS 156661-42-6)
- (4-Methylpentan-2-yl)({[1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl})amine dihydrochloride (CAS 1240528-12-4)
- (4-Isopropylpyridin-3-yl)methanol (CAS 1889904-97-5)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com