Betamethasone Impurity 124 CAS 947382-36-7
| CAS No. | 947382-36-7 |
| Molecular Formula | C22H27ClO4 |
| Molecular Weight | 390.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Betamethasone Impurity 124 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Betamethasone Impurity 124 (CAS 947382-36-7) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27ClO4 and a molecular weight of 390.90 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Betamethasone Impurity 124 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 390.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H27ClO4 |
| Molecular Weight | 390.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Betamethasone Standards
- Betamethasone impurity 100 (CAS CATO-C4X-1437100)
- Betamethasone impurity 49 (CAS CATO-C4X-143749)
- Betamethasone Impurity 57 (CAS 1257544-85-6)
- Betamethasone impurity 61 (CAS 1257544-84-5)
- Betamethasone Impurity 22 (CAS 2990-65-0)
- Betamethasone EP Impurity H (CAS 185613-71-2)
- Betamethasone Impurity 117 (CAS CATO-C4X-1437117)
- Betamethasone Impurity 145 (CAS CATO-C4X-1437145)
Recommended Standards
- PBB 37 (CAS 6683-35-8)
- Beclomethasone-Δ17,20 21-Aldehyde(E/Z Mixture) (CAS 1174035-77-8&1174035-80-3)
- 3,4',5-Tribromo-1,1'-biphenyl (CAS 72416-87-6)
- Hydroxyzine Impurity 5 (CAS 2469273-48-9)
- Azathioprine Impurity 18 (CAS 304441-06-3)
- Gadobutrol impurity 172 (CAS CATO-C4X-2120172)
- Ambroxol Impurity 92 (CAS CATO-C4X-108592)
- 4-Propoxypicolinimidamide hydrochloride (CAS 1179362-47-0)
- 2-(Bis(2-hydroxyethyl)amino)propanoic acid (CAS 41244-51-3)
- Fluvastatin Lactone (CAS 94061-83-3)
- 2-Bromo-1-(2-bromo-4,6-dimethylphenyl)ethan-1-one (CAS 1246471-30-6)
- (2-Fluorobenzyl)hydrazine Hydrochloride (CAS 1216246-45-5)
- 6-(3-Fluorophenyl)-3-(methoxycarbonyl)picolinic acid (CAS 1443288-13-8)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com