Betamethasone Impurity 22 CAS 2990-65-0

Description

The occurrence of Betamethasone Impurity 22 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Betamethasone Impurity 22 (CAS 2990-65-0) is a high-purity analytical reference standard with the molecular formula C22H29FO5 and a molecular weight of 392.46 g/mol.

Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Betamethasone Impurity 22 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 392.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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