Duloxetine Impurity 19 CAS 947686-09-1
| CAS No. | 947686-09-1 |
| Molecular Formula | C25H23NO3S |
| Molecular Weight | 417.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Duloxetine Impurity 19 (CAS 947686-09-1, C25H23NO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Duloxetine Impurity 19 (C25H23NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Duloxetine Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H23NO3S |
| Molecular Weight | 417.52 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Duloxetine Standards
- Duloxetine Impurity 49 (CAS 116817-79-9)
- Duloxetine USP Related Compound H (CAS 199191-66-7)
- Duloxetine Impurity 45 (CAS CATO-C4X-133645)
- Duloxetine Impurity (CAS 199191-67-8)
- Duloxetine Impurity 12 (CAS 32634-66-5)
- Duloxetine Impurity 13 (CAS 741693-79-8)
- Duloxetine 4-Hydroxy N-Methyl (CAS 1346601-61-3)
- Duloxetine Impurity (CAS 2680527-91-5)
Recommended Standards
- (E)-{2-[4-(diphenylmethyl)piperazin-1-yl]-1-(4-fluorophenyl)ethylidene}(methoxy)amine 551921-46-1 6N-502S (CAS 551921-46-1)
- N-(Benzo[d][1,3]dioxol-5-yl)-2-((5-(benzylthio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 477331-39-8)
- Darunavir Impurity 26 (CAS 1418639-27-6)
- N-(4-methoxyphenyl)-2-(2-((p-tolylthio)methyl)-1H-benzo[d]imidazol-1-yl)acetamide (CAS 339100-11-7)
- Upadacitinib Impurity 188 (CAS CATO-C4X-2405188)
- Meropenem Impurity 56 (CAS CATO-C4X-130956)
- Mepivacaine EP Impurity D (CAS CATO-C4X-19286)
- N-(3-(2-Ethoxyethyl)-6-methoxybenzo[d]thiazol-2(3H)-ylidene)-2-((2-morpholino-2-oxoethyl)thio)acetamide (CAS 905695-17-2)
- Methyl 5-bromo-2-fluoro-3-isopropoxybenzoate (CAS 2624417-08-7)
- 2-(4-((Isopropyl(methyl)amino)methyl)piperidin-1-yl)acetic acid (CAS 1353966-48-9)
- 1-(4-Fluoropiperidin-4-yl)-N-((5-methylpyrimidin-2-yl)methyl)methanamine hydrochloride (CAS 2306278-59-9)
- Tetrakis(acetonitrile)copper(I) Trifluoromethanesulfonate (CAS 58452-28-1)
- 3-(Benzyloxy)-2,2-dimethoxypropan-1-ol (CAS 40166-30-1)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com