Acotiamide Impurity 9 CAS 948053-83-6

Description

The occurrence of Acotiamide Impurity 9 is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Acotiamide Impurity 9 (CAS 948053-83-6) is a certified pharmaceutical impurity reference standard with the molecular formula C6H10N4OS and a molecular weight of 186.23 g/mol.

Owing to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system, Acotiamide Impurity 9 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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