Timolol Impurity 15 CAS 949293-84-9
| CAS No. | 949293-84-9 |
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Timolol Impurity 15 (CAS 949293-84-9, C5H6N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Timolol Impurity 15 (C5H6N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Timolol Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Timolol Standards
- Timolol Impurity 16 (CAS 214691-24-4)
- Timolol Impurity 27 (CAS CATO-C4X-149627)
- Timolol EP Impurity D (CAS 30165-97-0)
- Timolol EP Impurity G (K salt) (CAS 79844-78-3)
- Timolol EP Impurity G (CAS 75202-36-7)
- Timolol EP Impurity F (CAS 30165-96-9)
- Timolol Impurity 7 (CAS 30315-49-2)
- Timolol Impurity 14 (CAS 58827-68-2)
Recommended Standards
- Acotiamide Impurity 21 (CAS 118452-04-3)
- Benzenesulfonic Acid (CAS 98-11-3)
- Mirabegron Impurity 9 (CAS 29676-71-9)
- Dimethylphosphorodithioate (CAS 756-80-9)
- Famotidine Impurity 34 (CAS CATO-C4X-139234)
- Enzalutamide Impurity 5 (CAS 179232-29-2)
- Ruxolitinib Impurity 6 (CAS 1911644-32-0)
- 4-(4-Acetyl-3-hydroxy-2-propylphenoxy)butanoic Acid Ethyl Ester (CAS 88420-31-9)
- tert-Butyl 4-iodo-1H-pyrazole-3-carboxylate (CAS 1354704-09-8)
- Praseodymium(III) perchlorate (CAS 13498-07-2)
- 1,3-Dimethoxy-2-propanol (CAS 623-69-8)
- Acetylsalicylic Acid (CAS 50-78-2)
- L-Panthenol (CAS 74561-18-5)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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