Butylphthalide Impurity 65 CAS 950681-33-1
| CAS No. | 950681-33-1 |
| Molecular Formula | C12H13BrO2 |
| Molecular Weight | 269.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Butylphthalide Impurity 65 (CAS 950681-33-1, C12H13BrO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Butylphthalide Impurity 65 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Butylphthalide Impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13BrO2 |
| Molecular Weight | 269.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
Related Butylphthalide Standards
- Butylphthalide Impurity 63 (CAS 950681-35-3)
- Butylphthalide Impurity 64 (CAS 950681-49-9)
- Butylphthalide Impurity 66 (CAS 950681-46-6)
- Butylphthalide Impurity 73 (CAS CATO-C4X-181373)
- Butylphthalide Impurity 44 (CAS CATO-C4X-181344)
- Butylphthalide Impurity 36 (CAS 2245275-82-3)
- Butylphthalide Impurity 83 (CAS CATO-C4X-181383)
- Butylphthalide Impurity 29 (CAS CATO-C4X-181329)
Recommended Standards
- Abemaciclib Impurity 185 (CAS 871258-57-0)
- Ethyl 4-bromomethylcinnamate (CAS 60682-98-6)
- 5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole (CAS 1007235-31-5)
- Methyl 1-(4-(bromomethyl)phenyl)cyclopropanecarboxylate 873372-30-6 A1-09524 (CAS 873372-30-6)
- Cefaclor EP Impurity A Hydrochloride (CAS 25705-52-6)
- Doxofylline Impurity 36 (CAS CATO-C4X-151336)
- Estradiol Valerate EP Impurity H (CAS 1421283-56-8)
- 1-(Methylcarbamoyl)pyrrolidine-3-carboxylic acid (CAS 1342274-73-0)
- 3-Oxo-3H-benzo[f]chromene-2-carbonitrile (CAS 4352-88-9)
- 5-Methoxybenzo[d]thiazole-6-carboxylic acid (CAS 739365-25-4)
- 4-(Hydroxymethyl)benzenesulfonic acid (CAS 122855-96-3)
- 6-Methyl-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydrochloride (CAS 1260637-11-3)
- Nosiheptide (CAS 56377-79-8)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com