Minocycline EP Impurity D HCl CAS 95940-02-6
| CAS No. | 95940-02-6 |
| Molecular Formula | C21H23N3O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Minocycline EP Impurity D HCl is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Minocycline EP Impurity D HCl (CAS 95940-02-6), a pharmacopoeial impurity reference standard (molecular formula C21H23N3O7HCl, MW 465.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Minocycline EP Impurity D HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 465.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Minocycline EP Impurity D HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23N3O7 HCl |
| Molecular Weight | 465.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Minocycline Standards
- Minocycline Impurity N1 (CAS 10118-89-5)
- Minocycline (CAS 10118-90-8)
- Minocycline EP Impurity F (CAS 1075240-33-3)
- Minocycline Hydrochloride Dihydrate (CAS 128420-71-3)
- Minocycline EP Impurity H (CAS 1346598-44-4)
- Minocycline Hydrochloride (CAS 13614-98-7)
- Minocycline Impurity 26 (CAS 149934-16-7)
- Minocycline impurity 73 (CAS 156263-28-4)
Recommended Standards
- Etoricoxib impurity 54 (CAS 646459-47-4)
- Galanthamine Impurity 40 (CAS 31504-42-4)
- Roxithromycin EP Impurity J (CAS 134834-12-1)
- 2,2-Dimethyl-N-(pyrazin-2-ylmethyl)propan-1-amine (CAS 1342896-41-6)
- 3,4-Di(furan-2-yl)-1-(pyridin-2-yl)-5,6,7,8-tetrahydroisoquinoline (CAS 692729-85-4)
- Atrasentan Impurity 17 (CAS 1140616-98-3)
- 4-[4-(ethanesulfonyl)-2-nitrophenyl]morpholine 5-(Ethylsulphonyl)-2-(morpholin-4-yl)nitrobenzene 942474-41-1 Ethyl 4-(morpholin-4-yl)-3-nitrophenyl sulphone (CAS 942474-41-1)
- 1-(6-Chloropyridazin-3-yl)-4-methyl-1,4-diazepane (CAS 223796-04-1)
- 3-Bromo-4-(cyclopropylmethyl)phenol (CAS 1243284-07-2)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com