Sivelestat sodium impurity 35 CAS 99-77-5
| CAS No. | 99-77-5 |
| Molecular Formula | C6H4O7S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Sivelestat sodium impurity 35 (CAS 99-77-5, C6H4O7S2Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sivelestat sodium impurity 35 (C6H4O7S2Na) contains a carbohydrate-derived structure, a sulfone group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Sivelestat sodium impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4O7S2 2*Na |
| Molecular Weight | 275.20 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 2 |
Related Sivelestat Standards
- Sivelestat Impurity 17 (CAS 10167-30-3)
- Sivelestat Impurity 7 (CAS 1071827-84-3)
- Sivelestat Impurity 9 (CAS 1094231-79-4)
- Sivelestat (CAS 127373-66-4)
- Sivelestat sodium Impurity 5 (CAS 127373-95-9)
- Sivelestat Impurity 18 (CAS 150374-97-3)
- Sivelestat Impurity 13 (CAS 150374-98-4)
- Sivelestat sodium Impurity 2 (CAS 150374-99-5)
Recommended Standards
- Lenalidomide Impurity 1 (CAS 2197414-57-4)
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- Cortisone 21-Propionate (CAS 21795-16-4)
- 5-Methoxy-4-(3-nitrophenoxy)-2-phenylpyrimidine (CAS 478029-73-1)
- 3-Benzoylpicolinicacid (CAS 64362-32-9)
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- N-(3-Chloro-4-methylphenyl)-2-(4-methyl-6-oxopyrimidin-1(6H)-yl)acetamide (CAS 1203391-59-6)
- rel-tert-Butyl (2R,4R)-2-(aminomethyl)-4-methylpyrrolidine-1-carboxylate (CAS 1363381-52-5)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com