Aripiprazole Impurity 46 CAS CATO-C4X-100846
| CAS No. | CATO-C4X-100846 |
| Molecular Formula | C18H27Cl3N2O |
| Molecular Weight | 393.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Aripiprazole Impurity 46 (CAS CATO-C4X-100846) is a certified pharmaceutical impurity reference standard with the molecular formula C18H27Cl3N2O and a molecular weight of 393.78 g/mol.
Structurally, Aripiprazole Impurity 46 (C18H27Cl3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 393.78 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Aripiprazole Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27Cl3N2O |
| Molecular Weight | 393.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Aripiprazole Standards
- Aripiprazole Impurity 17 (CAS 1424857-89-5)
- Aripiprazole Impurity 49 (CAS 882880-12-8)
- Aripiprazole Impurity 60 (CAS CATO-C4X-100860)
- Aripiprazole Impurity 47 (CAS CATO-C4X-100847)
- Aripiprazole EP Impurity D (CAS 203395-82-8)
- Aripiprazole EP Impurity C (CAS 203395-81-7)
- Aripiprazole Impurity 76 (CAS CATO-C4X-100876)
- Aripiprazole Impurity N17 (CAS 1076199-56-8)
Recommended Standards
- N-(4-(5-Chlorobenzo[d]oxazol-2-yl)phenyl)-3-nitrobenzamide (CAS 331668-02-1)
- (E)-1-(1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-3-(dimethylamino)prop-2-en-1-one (CAS 339099-22-8)
- 6-Chloro-2-(2-((5-nitrofuran-2-yl)methylene)hydrazinyl)-4-phenylquinazoline (CAS 327039-18-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3,5-dimethylphenyl)-1H-pyrrole-2-carboxamide (CAS 338956-41-5)
- Mirogabalin Impurity N84 (CAS 2166206-19-3)
- Tegoprazan Impurity 59 (CAS CATO-C4X-229759)
- Acetaminophen Impurity 34 (CAS 146897-60-1)
- 1-(4-(Ethylamino)-2-(methylthio)pyrimidin-5-yl)ethanone (CAS 66116-75-4)
- 3-(Furan-3-yl)propan-1-ol (CAS 56859-92-8)
- Fmoc-3,5-diiodo-Tyr-OH (CAS 103213-31-6)
- 5-Hexenyl acetate (CAS 5048-26-0)
- 1-[(ethylcarbamoyl)amino]cyclopentane-1-carboxylic acid (CAS 954256-60-1)
- Quinolin-3-yl(2-(trifluoromethyl)phenyl)methanone (CAS 1187165-86-1)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com