Vonoprazan Impurity 49 CAS CATO-C4X-1020249
| CAS No. | CATO-C4X-1020249 |
| Molecular Formula | C12H12ClFN2 |
| Molecular Weight | 238.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, Vonoprazan Impurity 49 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 238.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Vonoprazan Impurity 49 (CAS CATO-C4X-1020249) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12ClFN2 and a molecular weight of 238.69 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vonoprazan Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClFN2 |
| Molecular Weight | 238.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 121 (CAS 13069-92-4)
- Vonoprazan Impurity 223 (CAS 13069-04-0)
- Vonoprazan Impurity 271 (CAS CATO-C4X-1020271)
- Vonoprazan Impurity 298 (CAS 103860-56-6)
- Vonoprazan Impurity 130 (CAS 881674-06-2)
- Vonoprazan Impurity 197 (CAS CATO-C4X-1020197)
- Vonoprazan Impurity 293 (CAS 3033403-71-0)
- Vonoprazan Impurity 136 (CAS CATO-C4X-1020136)
Recommended Standards
- Phenyl 5-chlorothiophene-2-carboxylate (CAS 866849-51-6)
- 4-(Acetylamino)benzenesulfonyl-d (CAS 1020718-84-6)
- Phenyl 3-chlorothiophene-2-carboxylate (CAS 866849-49-2)
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- Cabotegravir Impurity 21 (CAS 2883234-40-8)
- Napipitant Impurity 4 (CAS CATO-C4X-34854)
- Avanafil Impurity 3 (CAS 1364671-52-2)
- 4,5,6,7-Tetrachloro-2-(quinolin-2-yl)-1H-indene-1,3(2H)-dione (CAS 27908-75-4)
- (3,5-Dibromo-4-methoxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone (CAS 51073-13-3)
- tert-butyl (2R,3R)-3-hydroxy-2-methylazetidine-1-carboxylate (CAS 1638744-75-8)
- (S)-(9H-Fluoren-9-yl)methyl 3-aminopyrrolidine-1-carboxylate (CAS 1220669-36-2)
- 1-Bromopropyn-3-ol (CAS 2060-25-5)
- (4-Amino-2-methoxyphenoxy)acetamide (CAS 893766-30-8)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com