Vonoprazan Impurity 48 CAS CATO-C4X-1020248
| CAS No. | CATO-C4X-1020248 |
| Molecular Formula | C11H6BrFN2 |
| Molecular Weight | 265.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 265.08 g/mol gives Vonoprazan Impurity 48 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Vonoprazan Impurity 48 (CAS CATO-C4X-1020248, C11H6BrFN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vonoprazan Impurity 48 (C11H6BrFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vonoprazan Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6BrFN2 |
| Molecular Weight | 265.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 82 (CAS 106058-86-0)
- Vonoprazan Impurity 131 (CAS 881674-01-7)
- Vonoprazan Impurity 251 (CAS CATO-C4X-1020251)
- Vonoprazan Impurity 198 (CAS 887577-48-2)
- Vonoprazan Impuirty 144 (CAS 13069-02-8)
- Vonoprazan Impurity 167 (CAS CATO-C4X-1020167)
- Vonoprazan Impurity 243 (CAS CATO-C4X-1020243)
- Vonoprazan Fumarate Impurity 86 (CAS CATO-C4X-102086)
Recommended Standards
- Methyl 2-(4-bromo-5-fluoro-1H-pyrazol-1-yl)-2-methylpropanoate (CAS 2092077-14-8)
- 6-(2,3-Dichlorophenoxy)pyridine-3-carbonitrile (CAS 1016793-12-6)
- Methyl 2-(2-amino-5-bromothiazol-4-yl)-2-oxoacetate (CAS 914349-73-8)
- 4-bromo-1-(difluoromethoxy)-2-isopropylbenzene (CAS 1062616-03-8)
- Benserazide Impurity 5 (CAS CATO-C4X-14275)
- Ruilugoli lmpurity 131 (CAS CATO-C4X-2429131)
- Abrocitinib Impurity 20 (CAS CATO-C4X-288420)
- 5-Bromo-1-fluoro-3-iodo-2-methylbenzene (CAS 1807009-01-3)
- N-Methyl-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 477863-91-5)
- 2-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one (CAS 1285661-67-7)
- Ethyl 5-aminoindoline-1-carboxylate (CAS 1021106-45-5)
- 4,4-Difluoro-1,3-dimethyl-4-bora-3a,4a-diaza-s-indacene (CAS 154793-49-4)
- 2-(Ethylamino)-2-methyl-4-(4-methyl-1h-pyrazol-1-yl)butanamide (CAS 1249190-19-9)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com