Vonoprazan Impurity 251 CAS CATO-C4X-1020251
| CAS No. | CATO-C4X-1020251 |
| Molecular Formula | C11H7BrFNO |
| Molecular Weight | 268.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 268.08 g/mol gives Vonoprazan Impurity 251 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Vonoprazan Impurity 251 (CAS CATO-C4X-1020251) is a certified pharmaceutical impurity reference standard with the molecular formula C11H7BrFNO and a molecular weight of 268.08 g/mol.
The molecular framework of Vonoprazan Impurity 251 (C11H7BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vonoprazan Impurity 251 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7BrFNO |
| Molecular Weight | 268.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 131 (CAS 881674-01-7)
- Vonoprazan Impurity 82 (CAS 106058-86-0)
- Vonoprazan Impurity 48 (CAS CATO-C4X-1020248)
- Vonoprazan Impuirty 144 (CAS 13069-02-8)
- Vonoprazan Impurity 198 (CAS 887577-48-2)
- Vonoprazan Impurity 167 (CAS CATO-C4X-1020167)
- Vonoprazan Impurity 243 (CAS CATO-C4X-1020243)
- Vonoprazan Fumarate Impurity 86 (CAS CATO-C4X-102086)
Recommended Standards
- N-(5-Iodothiazol-2-yl)acetamide (CAS 252662-43-4)
- Methyl 4-iodocyclohexane-1-carboxylate (CAS 1222863-94-6)
- Methanone, (5-bromo-2-fluorophenyl)-1h-pyrrol-2-yl- (CAS 552331-21-2)
- 2-Iodo-7-methylnaphthalene (CAS 1261588-76-4)
- Dapagliflozin Impurity 135 (CAS CATO-C4X-1138135)
- Bisnorlipoic Impurity N1 (CAS 13125-44-5)
- Parecoxib sodium Impurity 10 (CAS 2229657-81-0)
- N,N-Dimethyl-N-(3,4,5-trimethoxy-benzyl)-ethane-1,2-diamine (CAS 626216-33-9)
- (4-Cyano-3-fluorophenyl) 4-propylbenzoate (CAS 86776-51-4)
- Erythromycin Sulfate (CAS 7184-72-7)
- 5-Chloro-2-[(furan-2-ylmethyl)amino]pyrimidine-4-carboxylic acid (CAS 1087792-09-3)
- 1-methyl-5-phenyl-1H-pyrrole-2-carboxylic acid (CAS 400715-83-5)
- Tenofovir Impurity 51 (CAS 60682-95-3)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com