Vonoprazan Impuirty 144 CAS 13069-02-8
| CAS No. | 13069-02-8 |
| Molecular Formula | C5H3Cl2NO4S2 |
| Molecular Weight | 276.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Vonoprazan Impuirty 144 (CAS 13069-02-8), a pharmacopoeial impurity reference standard (molecular formula C5H3Cl2NO4S2, MW 276.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution, Vonoprazan Impuirty 144 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl2NO4S2 |
| Molecular Weight | 276.12 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 251 (CAS CATO-C4X-1020251)
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Recommended Standards
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- Terbutaline Impurity 18 (CAS CATO-C4X-118318)
- Empagliflozin Impurity 95 (CAS 1459754-40-5)
- Apremilast Impurity 122 (CAS CATO-C4X-1009122)
- tert-Butyl 3-formyl-4-methylpiperidine-1-carboxylate (CAS 1201187-01-0)
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- 5-Ethynyl-2-methyl-3-nitropyridine (CAS 1228962-70-6)
- Methyl 2-fluoro-4-(methoxymethoxy)benzoate (CAS 2271443-02-6)
- 2-Methyl-1H-imidazo[4,5-b]pyridine-6-carbaldehyde (CAS 1367992-56-0)
- 1-Bromo-4-butoxy-3,5,-dichlorobenzene (CAS 1242070-95-6)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com