Carfilzomib Impurity 11 CAS 247068-82-2
| CAS No. | 247068-82-2 |
| Molecular Formula | C14H25NO4 |
| Molecular Weight | 271.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Carfilzomib Impurity 11 (C14H25NO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Carfilzomib Impurity 11 (CAS 247068-82-2) is a certified pharmaceutical impurity reference standard with the molecular formula C14H25NO4 and a molecular weight of 271.35 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carfilzomib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H25NO4 |
| Molecular Weight | 271.35 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Carfilzomib Standards
- Carfilzomib Impurity 75 (CAS 2381627-87-6)
- Carfilzomib Impurity 50 (CAS 129603-01-6)
- CarfilzomiB impurity 12 (CAS 100564-78-1)
- Carfilzomib Impurity 92 (CAS CATO-C4X-102292)
- Carfilzomib Impurity 47 (CAS 72080-89-8)
- Carfilzomib Impurity 87 (CAS CATO-C4X-102287)
- Carfilzomib Impurity 28 (CAS 143415-51-4)
- Carfilzomib Impurity 34 (CAS 247068-81-1)
Recommended Standards
- methyl 2-(4-((tert-butoxycarbonyl)amino)cyclohexyl)acetate (CAS 946716-17-2)
- trans-Methyl 4-((tert-butoxycarbonyl)(methyl)amino)cyclohexanecarboxylate (CAS 400899-07-2)
- Atorvastatin Impurity 140 (CAS CATO-C4X-1132140)
- trans-4-Cyanophenyl 4-propylcyclohexanecarboxylate (CAS 62439-33-2)
- Chlortalidone EP Impurity A (CAS 345930-32-7)
- Glycerol Impurity 35 (CAS 18371-75-0)
- Vonoprazan Impurity 235 (CAS CATO-C4X-1020235)
- N,N-dimethyl-6-(piperidin-4-yloxy)pyridine-3-carboxamide dihydrochloride (CAS 1955539-91-9)
- (R)-RS 56812 (hydrochloride) (CAS 143339-12-2)
- Argatroban Impurity 41 (CAS CATO-C4X-100741)
- Ethyl 2-azabicyclo[3.1.0]hexane-1-carboxylate hydrochloride (CAS 1427380-41-3)
- 5-(4-Chlorophenyl)-3-(2-(pyrrolidin-1-yl)ethoxy)-1H-pyrazole maleate (CAS 86871-55-8)
- 5-Iodospiro[indoline-3,2'-[1,3]dioxolan]-2-one (CAS 34058-27-0)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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