N-Nitroso Mitoxantrone Impurity 8 CAS CATO-C4X-10348
| CAS No. | CATO-C4X-10348 |
| Molecular Formula | C22H27N5O7 |
| Molecular Weight | 473.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, N-Nitroso Mitoxantrone Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 473.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, N-Nitroso Mitoxantrone Impurity 8 (CAS CATO-C4X-10348, C22H27N5O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), N-Nitroso Mitoxantrone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27N5O7 |
| Molecular Weight | 473.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related N Standards
- N1-Nitroso Mitoxantrone (CAS CATO-C4X-103412)
- N-Nitroso Minocycline EP Impurity C (CAS 28698-93-3)
- N-Nitroso Minocycline impurity 80 (CAS CATO-C4X-169980)
- N-Nitroso Dalpiciclib impurity 2 (CAS CATO-C4X-32952)
- N-Nitroso 2-Deamino-2-Hydroxyfolic acid (CAS CATO-C3D-262126)
- N-Nitroso Vilazodone (CAS CATO-C4X-135513)
- N-Nitroso Methotrexate EP Impurity B (CAS CATO-C4X-115449)
- N-Nitroso Folic acid EP Impurity C (CAS 29291-35-8)
Recommended Standards
- Azilsartan Impurity 110 (CAS CATO-C4X-1096110)
- tert-butyl 4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butanoate (CAS 2435783-77-8)
- Cefotaxime Impurity 16 (CAS CATO-C4X-120116)
- Temsavir (CAS 701213-36-7)
- Gadobutrol Impurity 9 (CAS 16695-22-0)
- Bisoprolol Impurity 36 (CAS 14697-49-5)
- Sofosbuvir Impurity 24 (CAS CATO-C4X-105224)
- 7-benzyl-1,3,7-triazaspiro[4.5]decane-2,4-dione (CAS 28937-10-2)
- 5-Methoxy-2-(methoxymethoxy)benzaldehyde (CAS 73220-20-9)
- 3-(tert-Butoxy)-3-oxo-2-(quinolin-4-ylmethyl)propanoic acid (CAS 1799439-14-7)
- 3-(Cyclohexylamino)propane-1,2-diol (CAS 53052-03-2)
- 1-(tert-Butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 180903-16-6)
- 2-(tert-Butoxy)-3-cyclopropoxy-4-ethylpyridine (CAS 1243315-91-4)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
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