Paroxetine Impurity 76 CAS CATO-C4X-103576
| CAS No. | CATO-C4X-103576 |
| Molecular Formula | 2*C25H24FNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Paroxetine Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Paroxetine Impurity 76 (CAS CATO-C4X-103576), a pharmacopoeial impurity reference standard (molecular formula C25H24FNO3HCl, MW 441.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C25H24FNO3HCl, Paroxetine Impurity 76 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 441.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | 2*C25H24FNO3 HCl |
| Molecular Weight | 441.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Metoclopramide Impurity 39 (CAS 81887-68-5)
- Rifapentine impurity 29 (CAS CATO-C4X-195929)
- Crotamiton Impurity 2 (CAS CATO-C4X-19562)
- (S)-3-(((2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)butanoyl)oxy)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 944283-12-9)
- 2-Methylamino-butyric acid (CAS 70606-05-2)
- 3-(pyrrolidin-1-yl)pyridine-4-carbonitrile (CAS 1461707-74-3)
- 1-Methyl-5-sulfamoyl-1H-pyrrole-2-carboxylic acid (CAS 306936-62-9)
- Methyl 2-amino-5-[3-(trifluoromethyl)phenyl]benzoate (CAS 926236-39-7)
- 3-Methoxy-2-(trifluoromethyl)pyridine-4-acetic acid (CAS 1227561-55-8)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
Why CATO?
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