Paroxetine Impurity G CAS CATO-C4X-103575
| CAS No. | CATO-C4X-103575 |
| Molecular Formula | 2*C25H24FNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Paroxetine Impurity G (CAS CATO-C4X-103575, C25H24FNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H24FNO3, Paroxetine Impurity G contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 405.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C25H24FNO3 |
| Molecular Weight | 405.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Aztreonam Impurity 106 (CAS CATO-C4X-1522106)
- Bisacodyl Impurity 24 (CAS CATO-C4X-203724)
- Encorafenib Impurity 4 (CAS CATO-C4X-32494)
- 3-(5-Ethyl-5-methylmorpholin-2-yl)benzoic acid (CAS 1513417-74-7)
- (2,5-dichlorothiophen-3-yl)methanol (CAS 219765-84-1)
- Ethyl 3-azabicyclo[3.3.1]nonane-1-carboxylate (CAS 1330766-09-0)
- Dysprosium(III) acetate (CAS 18779-07-2)
- O-2093 (CAS 439080-01-0)
- 2-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]acetic acid (CAS 22091-43-6)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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