Lorazepam Impurity 19 CAS CATO-C4X-104119
| CAS No. | CATO-C4X-104119 |
| Molecular Formula | C18H17Cl2NO3 |
| Molecular Weight | 366.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lorazepam Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Lorazepam Impurity 19 (CAS CATO-C4X-104119), a pharmacopoeial impurity reference standard (molecular formula C18H17Cl2NO3, MW 366.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lorazepam Impurity 19 (C18H17Cl2NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 366.24 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H17Cl2NO3 |
| Molecular Weight | 366.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lorazepam Standards
- Lorazepam Impurity 8 (CAS 2848-96-6)
- Lorazepam Impurity 20 (CAS CATO-C4X-104120)
- Lorazepam impurity 9 (CAS CATO-C4X-10419)
- Lorazepam Impurity 18 (CAS CATO-C4X-104118)
- Lorazepam-D4 (CAS 84344-15-0)
- Lorazepam Impurity 14 (CAS CATO-C4X-104114)
- Lorazepam Impurity 15 (CAS CATO-C4X-104115)
- Lorazepam-13C2,15N (CAS 907200-04-8)
Recommended Standards
- tert-butyl 1-(2-iodoethyl)-2,3,3a,4,6,6a-hexahydropyrrolo[3,4-b]pyrrole-5-carboxylate (CAS 2382885-74-5)
- Benzoylprop-Ethyl (CAS 22212-55-1)
- Propyl Gallate Impurity 1 (CAS 5693-34-5)
- Atpenin A5 (CAS 119509-24-9)
- Belumosudil Impurity 50 (CAS CATO-C4X-298850)
- Gadobutrol Impurity 11 (CAS 294-90-6)
- Ebastine EP Impurity E (CAS 1312211-93-0)
- 2,6-Dihydroxybenzamide (CAS 3147-50-0)
- Methyl 4-((4-hydroxypiperidin-1-yl)methyl)benzoate (CAS 415946-11-1)
- Corin (CAS 1808113-09-8)
- 2-(3-bromo-4-methylphenyl)-4-methyl-1,3-oxazole (CAS 1955520-18-9)
- Olaparib Impurity 84 (CAS CATO-C4X-113584)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-22-7)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com