Trelagliptin Impurity 49 CAS CATO-C4X-104649
| CAS No. | CATO-C4X-104649 |
| Molecular Formula | C23H29ClFN5O3 |
| Molecular Weight | 477.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Trelagliptin Impurity 49 (CAS CATO-C4X-104649), a pharmacopoeial impurity reference standard (molecular formula C23H29ClFN5O3, MW 477.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Trelagliptin Impurity 49 (C23H29ClFN5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trelagliptin Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H29ClFN5O3 |
| Molecular Weight | 477.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Trelagliptin Standards
- Trelagliptin Impurity 16 (CAS CATO-C4X-104616)
- Trelagliptin impurity 13 (CAS CATO-C4X-104613)
- Trelagliptin Impurity 70 (CAS CATO-C4X-104670)
- Trelagliptin Impurity 50 (CAS CATO-C4X-104650)
- Trelagliptin Impurity 2 (CAS CATO-C4X-10462)
- Trelagliptin Impurity 59 (CAS CATO-C4X-104659)
- Trelagliptin Impurity 36 (CAS CATO-C4X-104636)
- Trelagliptin Impurity 66 (CAS 1799608-63-1)
Recommended Standards
- Mosapride Impurity 61 (CAS CATO-C4X-104461)
- Etoricoxib Impurity 21 (CAS CATO-C4X-108021)
- N-((5-(N-(3-Chlorophenyl)sulfamoyl)-2-methylphenyl)carbamothioyl)-4-fluorobenzamide (CAS 379696-86-3)
- Etoricoxib Impurity 33 (CAS 1817735-82-2)
- Ibrutinib Impurity 21 (CAS CATO-C4X-106421)
- Rifamycin impurity 20 (CAS 32259-67-9)
- Verapamil EP Impurity B HCl (CAS 13078-76-7)
- 5-(2,2-Dihydroxyacetyl)-2-hydroxybenzoic acid (CAS 54440-92-5)
- 3-Amino-3-(3-hydroxy-4-methoxyphenyl)propanoic acid (CAS 129042-81-5)
- 2,4-Dichloro-N-[(1Z,3E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-{[(2,6-dichlorophenyl)methoxy]imino}prop-1-en-1-yl]aniline (CAS 320420-29-9)
- 2-(Difluoromethyl)-4,6-dimethoxypyridine (CAS 1805253-50-2)
- 5,6-dimethylpyridine-3-carboxylic acid (CAS 757903-81-4)
- N-(4-Methoxybenzyl)-2-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 1170243-00-1)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com