Ceritinib Impurity 6 CAS CATO-C4X-10486
| CAS No. | CATO-C4X-10486 |
| Molecular Formula | C23H27ClN4O3S |
| Molecular Weight | 475.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 475.00 g/mol gives Ceritinib Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ceritinib Impurity 6 (CAS CATO-C4X-10486), a pharmacopoeial impurity reference standard (molecular formula C23H27ClN4O3S, MW 475.00 g/mol) used for the identification and quantification of trace impurities in APIs.
Ceritinib Impurity 6 (C23H27ClN4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceritinib Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27ClN4O3S |
| Molecular Weight | 475.00 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 15 (CAS CATO-C4X-1048915)
- Ceritinib Impurity 63 (CAS CATO-C4X-104863)
- Ceritinib Impurity 62 (CAS CATO-C4X-104862)
- Ceritinib Impurity 4 (CAS CATO-C4X-10484)
- Ceritinib Impurity 3 (CAS CATO-C4X-10483)
- Ceritinib Impurity 54 (CAS CATO-C4X-104854)
- Ceritinib Impurity 5 (CAS CATO-C4X-10485)
- Ceritinib Impurity 12 (CAS CATO-C4X-104812)
Recommended Standards
- Bepotastine Impurity 22 (CAS CATO-C4X-183922)
- Nerandomilast impurity 10 (CAS CATO-C4X-347310)
- Avibactam Impurity 133 (CAS 1133931-73-3)
- 2,2'-(2,2'-Dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 2248640-53-9)
- Ofloxacin Impurity 9 (CAS CATO-C4X-17179)
- Sodium carbosulfonate impurity34 (CAS CATO-C4X-229134)
- Azilsartan Impurity 7 (CAS 1397836-49-5)
- 1,6-Dimethylchrysene (CAS 117022-39-6)
- 4-(Dimethoxy(methyl)silyl)aniline (CAS 113845-00-4)
- 3-((Azetidin-3-yloxy)methyl)-1-isopropyl-1h-pyrazole (CAS 1340036-16-9)
- N-(4-Chloro-3-(trifluoromethoxy)phenyl)acetamide (CAS 7574-46-1)
- Tavaborole Impurity 23 (CAS 345-29-9)
- 2-Oxa-7-azaspiro[4.4]Nonane-9-carboxylic acid (CAS 1341929-36-9)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com