Sofosbuvir Impurity 8 CAS CATO-C4X-10528
| CAS No. | CATO-C4X-10528 |
| Molecular Formula | C31H26FN3O7 |
| Molecular Weight | 571.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sofosbuvir Impurity 8.
CATO supplies Sofosbuvir Impurity 8 (CAS CATO-C4X-10528), a pharmacopoeial impurity reference standard (molecular formula C31H26FN3O7, MW 571.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C31H26FN3O7, Sofosbuvir Impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 571.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H26FN3O7 |
| Molecular Weight | 571.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 10 (CAS CATO-C4X-105210)
- Sofosbuvir Impurity 11 (CAS CATO-C4X-105211)
- Sofosbuvir Impurity 4 (CAS 874638-94-5)
- Sofosbuvir Impurity 5 (CAS CATO-C4X-10525)
- Sofosbuvir Impurity 6 (CAS CATO-C4X-10526)
- Sofosbuvir Impurity 7 (CAS CATO-C4X-10527)
- Sofosbuvir Impurity 72 (CAS CATO-C4X-105272)
- Sofosbuvir Impurity 81 (CAS CATO-C4X-105281)
Recommended Standards
- Sofosbuvir Impurity 82 (CAS CATO-C4X-105282)
- Sofosbuvir Impurity 87 (CAS 817204-32-3)
- Sofosbuvir Impurity 9 (CAS 2173637-26-6)
- SN-38-d3 Glucuronide (CAS CATO-C4X-15717)
- Azilsartan Impurity 123 (CAS CATO-C4X-1096123)
- Linagliptin Impurity 58 (CAS CATO-C4X-110158)
- Baclofen Impurity 62 (CAS CATO-C4X-101262)
- (R)-N-methyl-1-(4-methylmorpholin-2-yl)methanamine (CAS 1268521-53-4)
- 2-Fluoro-3-methoxynaphthalen-1-ol (CAS 2158300-64-0)
- N-(6-methylpyridin-2-yl)-2-nitrobenzamide (CAS 326901-31-9)
- 5,5'-(Carbonylbis(azanediyl)bis(methylene))bis(3-fluoro-5,1-phenylene)diboronic acid (CAS 2377606-23-8)
- Baricitinib Impurity 23 (CAS 1146629-75-5)
- (S)-2-(((tert-Butoxycarbonyl)amino)methyl)-4-methylpentanoic acid (CAS 828254-18-8)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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