Linagliptin Impurity 58 CAS CATO-C4X-110158
| CAS No. | CATO-C4X-110158 |
| Molecular Formula | C20H18N6O3 |
| Molecular Weight | 390.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Linagliptin Impurity 58 (C20H18N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Linagliptin Impurity 58 (CAS CATO-C4X-110158), a pharmacopoeial impurity reference standard (molecular formula C20H18N6O3, MW 390.40 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18N6O3 |
| Molecular Weight | 390.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Linagliptin Standards
- Linagliptin impurity 152 (CAS CATO-C4X-1101152)
- Linagliptin impurity 116 (CAS CATO-C4X-1101116)
- Linagliptin impurity 125 (CAS CATO-C4X-1101125)
- Linagliptin impurity 140 (CAS 2428491-17-0)
- Linagliptin Impurity 4 (CAS 2749405-42-1)
- Linagliptin Impurity 49 (CAS CATO-C4X-110149)
- Linagliptin Impurity 47 (CAS 2468656-63-3)
- Linagliptin impurity 118 (CAS CATO-C4X-1101118)
Recommended Standards
- N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-6-yl)-2-(trifluoromethyl)benzamide (CAS 946289-30-1)
- Flurbiprofen Impurity 116 (CAS CATO-C4X-1444116)
- N-(1-Isobutyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(trifluoromethyl)benzamide (CAS 941991-52-2)
- Fluvoxamine Impurity 36 (CAS CATO-C4X-195136)
- Trelagliptin Impurity 12 (CAS CATO-C4X-104612)
- Ruxolitinib Impurity 66 (CAS CATO-C4X-205866)
- Dexamethasone EP Impurity I (CAS 14622-47-0)
- 1-Bromo-4-[(1E)-4-bromobut-1-en-1-yl]benzene (CAS 1190898-63-5)
- n-(3-Aminopropyl)-n-methylcyclohexanamine (CAS 26735-20-6)
- 4-[(carbamoylamino)methyl]benzoic acid (CAS 2372-49-8)
- 2-Amino-N-(2-chloropyridin-3-yl)benzamide (CAS 956-30-9)
- 6-Chloro-3-methylpyridin-2-carbonitrile (CAS 1201924-31-3)
- 3-Iodo-4-((4-methylbenzyl)oxy)benzonitrile (CAS 1706459-19-9)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com