Bromhexine impurity 65 CAS CATO-C4X-106065
| CAS No. | CATO-C4X-106065 |
| Molecular Formula | C20H30Br2N2O5 |
| Molecular Weight | 538.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bromhexine impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Bromhexine impurity 65 (CAS CATO-C4X-106065, C20H30Br2N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bromhexine impurity 65 (C20H30Br2N2O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H30Br2N2O5 |
| Molecular Weight | 538.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromhexine Standards
- Bromhexine D-Glucose Derivative (CAS CATO-C4X-106021)
- Bromhexine Impurity 26 (CAS CATO-C4X-106026)
- Bromhexine Impurity 31 (CAS CATO-C4X-106031)
- Bromhexine L-Glucose Derivative(Mixture of Diastereomers) (CAS CATO-C4X-106032)
- Bromhexine Impurity 37 (CAS CATO-C4X-106037)
- Bromhexine Impurity 64 (CAS CATO-C4X-106064)
- Bromhexine impurity 67 (CAS CATO-C4X-106067)
- Bromhexine L-Glucose Derivative (CAS CATO-C4X-106043)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com