Ibrutinib Impurity 129 CAS CATO-C4X-1064129
| CAS No. | CATO-C4X-1064129 |
| Molecular Formula | C24H21N5O |
| Molecular Weight | 395.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ibrutinib Impurity 129 (CAS CATO-C4X-1064129), a pharmacopoeial impurity reference standard (molecular formula C24H21N5O, MW 395.46 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ibrutinib Impurity 129 (C24H21N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibrutinib Impurity 129 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H21N5O |
| Molecular Weight | 395.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Ibrutinib Standards
- Ibrutinib Impurity 158 (CAS CATO-C4X-1064158)
- Ibrutinib Impurity 136 (CAS 2190506-59-1)
- Ibrutinib Impurity 140 (CAS CATO-C4X-1064140)
- Ibrutinib Impurity 35 (CAS CATO-C4X-106435)
- Ibrutinib Impurity 174 (CAS CATO-C4X-1064174)
- Ibrutinib Impurity 10 (CAS 1022150-12-4)
- Ibrutinib Impurity 24 (CAS 330785-90-5)
- Ibrutinib Impurity 25 (CAS CATO-C4X-106425)
Recommended Standards
- N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine (CAS 202272-68-2)
- Imatinib Impurity 96 (CAS 152459-96-6)
- N-(6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(furan-2-yl)pyrimidin-4-yl)-2-(4-methylpiperazin-1-yl)acetamide (CAS 912940-20-6)
- 4-Isopropoxy-N-(5-oxido-2-phenyl-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)benzamide (CAS 1020247-90-8)
- Difamilast Impurity 2 (CAS 2103190-94-7)
- Amisulpride Impurity 32 (CAS CATO-C4X-104532)
- Flurbiprofen Impurity 36 (CAS CATO-C4X-144436)
- 4-Bromo-2-(2-bromoethyl)thiophene (CAS 1343682-34-7)
- (3R,4R)-3-[2,6-Bis(acetyloxy)-4-pentylphenyl]-4-(1-methylethenyl)-1-cyclohexene-1-carboxaldehyde (CAS 380495-74-9)
- 11-Cyano-N-(4-nitrophenyl)-9,10-dihydro-9,10-ethanoanthracene-11-carboxamide (CAS 312505-69-4)
- 3-Iodo-N'-phenylbenzohydrazide (CAS 74305-97-8)
- trans,cis-1,9-Cyclohexadecadiene (CAS 110028-14-3)
- (2-Chloro-1,3-thiazol-5-yl)methyl 2-methylbenzoate (CAS 672949-83-6)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com