Empagliflozin Impurity 80 CAS CATO-C4X-106580
| CAS No. | CATO-C4X-106580 |
| Molecular Formula | C14H9ClFIO |
| Molecular Weight | 374.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Empagliflozin Impurity 80 (CAS CATO-C4X-106580), a pharmacopoeial impurity reference standard (molecular formula C14H9ClFIO, MW 374.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, a polycyclic aromatic system, Empagliflozin Impurity 80 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Empagliflozin Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClFIO |
| Molecular Weight | 374.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 242 (CAS CATO-C4X-1065242)
- Empagliflozin impurity 246 (CAS CATO-C4X-1065246)
- Empagliflozin impurity 251 (CAS CATO-C4X-1065251)
- Empagliflozin Impurity 81 (CAS CATO-C4X-106581)
- Empagliflozin Impurity 305 (CAS CATO-C4X-1065305)
- Empagliflozin Impurity 102 (CAS CATO-C4X-1065102)
- Empagliflozin impurity 208 (CAS CATO-C4X-1065208)
- Empagliflozin Impurity 146 (CAS CATO-C4X-1065146)
Recommended Standards
- N,N,N',N'-tetraethyl-1,1-bis(phenylethynyl)silanediamine (CAS 189632-30-2)
- tert-Butyl (R)-3-((2-((tert-butyldimethylsilyl)oxy)ethoxy)methyl)piperazine-1-carboxylate (CAS 2798809-28-4)
- tert-Butyl (3-bromo-5-chloro-4-(trifluoromethyl)phenyl)carbamate (CAS 2803281-61-8)
- tert-Butyl (S)-3-((2-((tert-butyldimethylsilyl)oxy)ethoxy)methyl)piperazine-1-carboxylate (CAS 2798809-30-8)
- Ilaprazole Impurity 125 (CAS CATO-C4X-1130125)
- Empagliflozin impurity 270 (CAS CATO-C4X-1065270)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
- 4-Amino-n-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride (CAS 52423-58-2)
- Difelikefalin Impurity 104 (CAS CATO-C4X-3041104)
- (3-Chloro-4-((2,6-dimethylpyridin-3-yl)oxy)phenyl)boronic acid pinacol ester, 97% (CAS 1362703-38-5)
- Boc-isonipecotic acid (CAS 84358-13-4)
- 1-[(2-chlorophenyl)methyl]-1H-pyrazole (CAS 202344-35-2)
- N-[(2H-1,3-Benzodioxol-5-yl)methyl]-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775541-77-9)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com