Erlotinib Impurity 39 CAS CATO-C4X-106939
| CAS No. | CATO-C4X-106939 |
| Molecular Formula | C22H23N3O4 |
| Molecular Weight | 393.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Erlotinib Impurity 39.
CATO supplies Erlotinib Impurity 39 (CAS CATO-C4X-106939), a pharmacopoeial impurity reference standard (molecular formula C22H23N3O4, MW 393.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Erlotinib Impurity 39 (C22H23N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 393.44 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Erlotinib Impurity 39 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O4 |
| Molecular Weight | 393.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib (CAS 183321-74-6)
- Erlotinib Impurity 55 (CAS 2410548-57-9)
- Erlotinib Impurity 96 (CAS CATO-C4X-106996)
- Erlotinib metabolite M11 (CAS 882172-60-3)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 103 (CAS 299912-61-1)
- Erlotinib Impurity 2 (CAS 183321-85-9)
Recommended Standards
- Valsartan Impurity 111 (CAS CATO-C4X-1057111)
- 4-(benzylamino)-6-(4-methoxyphenyl)-2-(4-pyridinyl)-5-pyrimidinecarbonitrile 400078-50-4 KS-000033IM (CAS 400078-50-4)
- Tryptophan EP Impurity J (CAS 164068-19-3)
- N-(4-Isopropylphenyl)-2-(4-(4-methoxybenzylidene)-2,5-dioxoimidazolidin-1-yl)acetamide (CAS 867311-85-1)
- Naltrexone impurity 43 (CAS CATO-C4X-147543)
- Domperidone Impurity N8 (CAS 58859-46-4)
- Linagliptin impurity 137 (CAS CATO-C4X-1101137)
- 4-Cyano-1H-1,2,3-triazole-5-carboxamide (CAS 57613-19-1)
- 2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-chlorobenzaldehyde (CAS 1242156-60-0)
- 2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)-2-(methylthio)acetic acid (CAS 1353957-76-2)
- N-(4-(Dimethylamino)benzyl)-1,5-dimethyl-1H-pyrazol-4-amine dihydrochloride (CAS 1856092-84-6)
- 4-cyclopropyl-2-methylpyrimidin-5-amine (CAS 1368136-90-6)
- 5-Fluoro-7-methyl-1H-indazole (CAS 1427377-45-4)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com