Tofacitinib Impurity 120 CAS CATO-C4X-1079120
| CAS No. | CATO-C4X-1079120 |
| Molecular Formula | C18H27N5O |
| Molecular Weight | 329.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Tofacitinib Impurity 120 (CAS CATO-C4X-1079120, C18H27N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H27N5O, Tofacitinib Impurity 120 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Tofacitinib Impurity 120 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27N5O |
| Molecular Weight | 329.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tofacitinib Standards
- Tofacitinib Impurity 17 (CAS 1675248-19-7)
- Tofacitinib Impurity 73 (CAS CATO-C4X-107973)
- Tofacitinib Impurity 119 (CAS 2407039-29-4)
- Tofacitinib Impurity 139 (CAS CATO-C4X-1079139)
- Tofacitinib Impurity 159 (CAS 1640971-51-2)
- Tofacitinib Impurity 171 (CAS CATO-C4X-1079171)
- Tofacitinib Impurity 231 (CAS 2101951-20-4)
- Tofacitinib Impurity 27 (CAS 2028267-73-2)
Recommended Standards
- New fuchsine (free base) (CAS 25739-74-6)
- Lasmiditan Impurity 50 (CAS CATO-C4X-247850)
- N-Decyl-3-nitroquinolin-4-amine (CAS 63010-97-9)
- All-trans Acitretin-D3 (CAS 1185241-03-5)
- Tinidazole EP Impurity A (CAS 696-23-1)
- Cefodizime Impurity 15 (CAS CATO-C4X-180615)
- Oseltamivir Impurity 112 (CAS CATO-C4X-1720112)
- 1-Benzyl-4-(piperidin-1-yl)phthalazine (CAS 304885-21-0)
- 4-(Azidomethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole (CAS 1325304-01-5)
- 7-Methyl-2-(pyridin-4-yl)indoline (CAS 595547-36-7)
- 2-Phenyl-6-(trifluoromethyl)quinolin-4-amine (CAS 1189106-21-5)
- 2,4-Dimethyl-5-oxazolecarboxylic Acid (CAS 2510-37-4)
- 4-(N-Boc-Amino)-5-(methoxycarbonyl)thiophene-2-boronic acid (CAS 2377608-25-6)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com