Tofacitinib Nitroso Impurity 187 CAS CATO-C4X-1079187
| CAS No. | CATO-C4X-1079187 |
| Molecular Formula | C13H20N6O |
| Molecular Weight | 276.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tofacitinib Nitroso Impurity 187 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tofacitinib Nitroso Impurity 187 (CAS CATO-C4X-1079187) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20N6O and a molecular weight of 276.34 g/mol.
Tofacitinib Nitroso Impurity 187 (C13H20N6O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H20N6O |
| Molecular Weight | 276.34 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tofacitinib Standards
- Tofacitinib Impurity N48 (CAS 1638499-35-0)
- Tofacitinib Impurity 242 (CAS CATO-C4X-1079242)
- Tofacitinib Nitroso Impurity 188 (CAS CATO-C4X-1079188)
- Tofacitinib Impurity 158 (CAS CATO-C4X-1079158)
- Tofacitinib Impurity 203 (CAS CATO-C4X-1079203)
- Tofacitinib Impurity 111 (CAS 2183519-70-0)
- Tofacitinib Impurity 114 (CAS CATO-C4X-1079114)
- Tofacitinib Impurity 22 (CAS 2227199-28-0)
Recommended Standards
- N1-[(1E)-(4-Methylphenyl)methylene]-4-phenyl-1H-imidazole-1,2-diamine (CAS 1993648-80-8)
- Methyl 1-(1,3-benzothiazol-2-yl)piperidine-4-carboxylate (CAS 1031498-32-4)
- N,N-Dimethyl-3,6-diphenyl-1,2,4-triazin-5-amine (CAS 339013-08-0)
- 1-[4-(Aminomethyl)phenyl]-N-phenylmethanesulfonamide (CAS 1041556-68-6)
- N-Nitroso Tamsulosin Impurity (Mixture of Isomers) (CAS CATO-C3D-5990)
- Lifitegrast Impurity 90 (CAS CATO-C4X-240990)
- Irbesartan Impurity 41 (CAS CATO-C4X-166641)
- 6-Bromo-2-difluoromethoxy-3-methylpyridine (CAS 1807116-08-0)
- 2-(6-Chloro-3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)acetyl chloride (CAS 875006-82-9)
- 14-Methylpentadec-1-ene-3,10-dione (CAS 32746-63-7)
- 18A (CAS 331261-50-8)
- Ethyl 4-(2,6-dichlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 866143-59-1)
- (4-Methyl-3-phenyl-1H-pyrrol-2-yl)methanol (CAS 188716-78-1)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
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