Tofacitinib Nitroso Impurity 188 CAS CATO-C4X-1079188

Description

As a certified reference material (CRM), Tofacitinib Nitroso Impurity 188 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Tofacitinib Nitroso Impurity 188 (CAS CATO-C4X-1079188) is a certified pharmaceutical impurity reference standard with the molecular formula C13H22N6O and a molecular weight of 278.35 g/mol.

Structurally, Tofacitinib Nitroso Impurity 188 (C13H22N6O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 278.35 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

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