Tofacitinib Impurity 202 CAS CATO-C4X-1079202
| CAS No. | CATO-C4X-1079202 |
| Molecular Formula | C20H24N6O |
| Molecular Weight | 364.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tofacitinib Impurity 202 (CAS CATO-C4X-1079202) is a certified pharmaceutical impurity reference standard with the molecular formula C20H24N6O and a molecular weight of 364.44 g/mol.
Based on its molecular formula C20H24N6O, Tofacitinib Impurity 202 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 364.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tofacitinib Impurity 202 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N6O |
| Molecular Weight | 364.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tofacitinib Standards
- Tofacitinib Impurity 51 (CAS 2504210-38-0)
- Tofacitinib Impurity 150 (CAS 1616761-01-3)
- Tofacitinib Impurity 84 (CAS 1675248-18-6)
- Tofacitinib Impurity 134 (CAS CATO-C4X-1079134)
- Tofacitinib Impurity 135 (CAS CATO-C4X-1079135)
- Tofacitinib Impurity 136 (CAS 2803420-43-9)
- Tofacitinib Impurity 214 (CAS CATO-C4X-1079214)
- Tofacitinib Impurity 223 (CAS CATO-C4X-1079223)
Recommended Standards
- (S)-Ethyl 2-(N-benzyl-2-(tert-butoxycarbonylamino)-propanamido)acetate 86666-85-5 (CAS 86666-85-5)
- Gefitinib Impurity 32 (CAS CATO-C4X-111732)
- 68578-79-0 4,4'-(1,2-Diphenylethene-1,2-diyl)diphenol DTXSID50712287 (CAS 68578-79-0)
- Rosuvastatin Impurity 234 (CAS CATO-C4X-1169234)
- Ezetimibe Impurity N13 (CAS 1185883-40-2)
- Levocetirizine Impurity 43 (CAS 1116338-10-3)
- Esmolol Impurity 56 (CAS CATO-C4X-189156)
- 2-Amino-N-(2-bromophenyl)benzamide (CAS 34489-85-5)
- Methyl 3-aminoimidazo[1,2-a]pyridine-5-carboxylate (CAS 111753-15-2)
- Ketorolac Impurity 34 (CAS CATO-C4X-166934)
- 4-Allylpiperidin-4-amine (CAS 919112-84-8)
- Methyl 2,3,4,5-tetrahydro-1H-benzo[c]azepine-8-carboxylate (CAS 1397226-03-7)
- 5-Phenyl-1,2,3,4-tetrahydroquinoline (CAS 1501859-28-4)
- Dulaglutide (CAS 923950-08-7)
Why CATO?
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