Tofacitinib Impurity 213 CAS CATO-C4X-1079213
| CAS No. | CATO-C4X-1079213 |
| Molecular Formula | C27H30ClN5O2S |
| Molecular Weight | 524.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tofacitinib Impurity 213 (CAS CATO-C4X-1079213), a pharmacopoeial impurity reference standard (molecular formula C27H30ClN5O2S, MW 524.08 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H30ClN5O2S, Tofacitinib Impurity 213 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 524.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H30ClN5O2S |
| Molecular Weight | 524.08 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Tofacitinib Standards
- Tofacitinib Impurity 205 (CAS 2459302-87-3)
- Tofacitinib Impurity 173 (CAS CATO-C4X-1079173)
- Tofacitinib Impurity 222 (CAS CATO-C4X-1079222)
- Tofacitinib Impurity 49 (CAS 2459302-78-2)
- Tofacitinib Impurity 35 (CAS CATO-C4X-107935)
- Tofacitinib Impurity 36 (CAS CATO-C4X-107936)
- Tofacitinib Impurity 56 (CAS 923036-30-0)
- Tofacitinib Impurity 64 (CAS 2504210-40-4)
Recommended Standards
- 1-IOdo-1h,1h,2h,2h-perfluorononane (CAS 2043-52-9)
- Tris(4-(bromomethyl)phenyl)amine (CAS 100693-36-5)
- 1H,1H,2H,2H-Perfluoro-7-methyloctyliodide (CAS 18017-20-4)
- Loratadine Impurity 58 (CAS CATO-C4X-142658)
- Imipenem impurity 134 (CAS CATO-C4X-1662134)
- Tetrabenazine Impurity 68 (CAS CATO-C4X-274868)
- Iodixanol EP Impurity C (CAS 171897-74-8)
- 2-Chloro-5-(trifluoromethyl)pyridine (CAS 52334-81-3)
- tert-Butyl ((3S,5S)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate (CAS 663948-85-4)
- 3-((4h-1,2,4-Triazol-4-yl)methyl)benzenesulfonyl chloride (CAS 1537287-45-8)
- 1-(1,3-Benzodioxol-5-yl)-2-(methyl-d3-amino)-1-butanone (CAS 1231819-31-0)
- (E)-4-((3,5-Dibromo-2-hydroxybenzyl)oxy)-4-oxobut-2-enoic acid (CAS 93705-06-7)
- H-Phe-Phe-Phe-Phe-OH (CAS 2667-02-9)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com