Loratadine Impurity 58 CAS CATO-C4X-142658
| CAS No. | CATO-C4X-142658 |
| Molecular Formula | C30H38ClN3O3 |
| Molecular Weight | 524.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Loratadine Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Loratadine Impurity 58 (CAS CATO-C4X-142658), a pharmacopoeial impurity reference standard (molecular formula C30H38ClN3O3, MW 524.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Loratadine Impurity 58 (C30H38ClN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C30H38ClN3O3 |
| Molecular Weight | 524.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 46 (CAS CATO-C4X-142646)
- Loratadine Impurity 60 (CAS CATO-C4X-142660)
- Loratadine Impurity 48 (CAS CATO-C4X-142648)
- Loratadine Impurity 64 (CAS CATO-C4X-142664)
- Loratadine Impurity 62 (CAS CATO-C4X-142662)
- Loratadine Impurity 42 (CAS CATO-C4X-142642)
- Loratadine Impurity 44 (CAS CATO-C4X-142644)
- Loratadine Impurity 54 (CAS CATO-C4X-142654)
Recommended Standards
- Tris(4-(bromomethyl)phenyl)amine (CAS 100693-36-5)
- 2-((3-(4-Chlorophenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(2-isopropylphenyl)acetamide (CAS 477313-44-3)
- Tofacitinib Impurity 213 (CAS CATO-C4X-1079213)
- 5-((4-Chlorophenyl)thio)-4-(4-methoxyphenyl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)thiazole (CAS 685107-96-4)
- Lenalidomide Impurity 34 (CAS CATO-C4X-190334)
- Emtricitabine Dimer Impurity (CAS CATO-C4X-123215)
- Darolutamide Impurity 42 (CAS CATO-C4X-310642)
- 3-isopropyl-5-methylsulfanyl-1,6-dihydropyrazolo[4,3-d]pyrimidin-7-one (CAS 1289139-29-2)
- 2-(2-(3-Chloro-4-fluorophenoxy)ethyl)-1,3-dioxolane (CAS 1443354-15-1)
- 3-Chloro-5-isopropyl-1,2,4-oxadiazole (CAS 1243250-26-1)
- 1-(((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one (CAS 315692-82-1)
- 7-(Trifluoromethyl)-2-azabicyclo[4.1.0]Heptane (CAS 1311569-58-0)
- 5-Bromo-6-chloropyridine-3-sulfonyl Chloride (CAS 216394-05-7)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com