Tofacitinib Impurity 217 CAS CATO-C4X-1079217
| CAS No. | CATO-C4X-1079217 |
| Molecular Formula | C20H24ClN5O |
| Molecular Weight | 385.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tofacitinib Impurity 217 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Tofacitinib Impurity 217 (CAS CATO-C4X-1079217), a pharmacopoeial impurity reference standard (molecular formula C20H24ClN5O, MW 385.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tofacitinib Impurity 217 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 385.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H24ClN5O |
| Molecular Weight | 385.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Tofacitinib Standards
- Tofacitinib Impurity 50 (CAS 2227199-31-5)
- Tofacitinib Impurity 95 (CAS CATO-C4X-107995)
- Tofacitinib Impurity 26 (CAS CATO-C4X-107926)
- Tofacitinib Impurity 15 (CAS 2459302-77-1)
- Tofacitinib Impurity 67 (CAS CATO-C4X-107967)
- Tofacitinib Impurity 148 (CAS CATO-C4X-1079148)
- Tofacitinib Impurity 229 (CAS CATO-C4X-1079229)
- Tofacitinib Impurity 134 (CAS CATO-C4X-1079134)
Recommended Standards
- N3-(tert-butyl)-N2-(4-chlorophenyl)-3,4-dihydroisoquinoline-2,3(1H)-dicarboxamide (CAS 318256-30-3)
- 1,5-Dibromo-2-difluoromethoxy-3-(trifluoromethoxy)benzene (CAS 1803715-30-1)
- N3-(tert-butyl)-N2-(3-chlorophenyl)-3,4-dihydroisoquinoline-2,3(1H)-dicarboxamide (CAS 318517-16-7)
- 1,3-Dibromo-2-difluoromethoxy-5-(trifluoromethoxy)benzene (CAS 1803789-38-9)
- Moxifloxacin impurity 181 (CAS 1363407-28-6)
- Upadacitinib Impurity 216 (CAS CATO-C4X-2405216)
- Hyoscyamine Impurity 5 (CAS CATO-C4X-34375)
- 1,3-benzodioxole-4,5-dicarbaldehyde (CAS 52315-62-5)
- 2-(4-(Pyrimidin-2-yl)phenyl)ethanethiol (CAS 545424-24-6)
- 2-(4-Fluorophenyl)propane-1,3-diamine dihydrochloride (CAS 78533-97-8)
- 2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione (CAS 875440-38-3)
- 2-Amino-1-(3-chloro-2-fluorophenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 1094279-46-5)
- 2-bromo-1-(chloromethyl)-3,4-dimethoxybenzene (CAS 7477-50-1)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com