Ibuprofen Impurity 152 CAS CATO-C4X-1082152
| CAS No. | CATO-C4X-1082152 |
| Molecular Formula | C19H30O7 |
| Molecular Weight | 370.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ibuprofen Impurity 152.
As a process- or degradation-related impurity, Ibuprofen Impurity 152 (CAS CATO-C4X-1082152, C19H30O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ibuprofen Impurity 152 (C19H30O7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ibuprofen Impurity 152 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H30O7 |
| Molecular Weight | 370.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibuprofen Standards
- Ibuprofen impurity 118 (CAS CATO-C4X-1082118)
- Ibuprofen Impurity 126 (CAS CATO-C4X-1082126)
- Ibuprofen Impurity 48 (CAS CATO-C4X-108248)
- Ibuprofen Impurity 159 (CAS 1957156-46-5)
- Ibuprofen Impurity 160 (CAS 2664846-43-7)
- Ibuprofen Impurity 161 (CAS 1928708-57-9)
- Ibuprofen Acyl Glucuronide (Mixture of Diastereomers) (CAS 115075-59-7)
- Ibuprofen impurity 128 (CAS CATO-C4X-1082128)
Recommended Standards
- Plerixafor Impurity 20 (CAS 6315-52-2)
- Sulindac EP Impurity D (CAS 134439-52-4)
- N-Nitroso Propafenone (CAS 3036581-87-7)
- (1-trityl-1H-imidazole-4,5-diyl)dimethanol 77134-74-8 [4-(hydroxymethyl)-1-trityl-1H-imidazol-5-yl]methanol (CAS 77134-74-8)
- Sitagliptin Impurity 78 (Nitroso-STG-19) (NTTP) (CAS 2892260-32-9)
- Octreotide Impurity 33 (CAS CATO-C4X-152033)
- Rosuvastatin Impurity 169 (CAS 404958-69-6)
- Hexahydropyrrolo[1,2-a]pyrimidin-2(1H)-one (CAS 201228-87-7)
- Oxazole, 2,2′-(2,3-naphthalenediyl)bis[4,5-dihydro-4-(2-methylpropyl)-, (4S,4′S)- (CAS 591754-03-9)
- 2-[(4-Benzylpiperazin-1-yl)methyl]-2H,3H,5H,6H-imidazo[1,2-c]quinazolin-5-one (CAS 145938-38-1)
- Ethyl 3-amino-5-fluoro-2-methylbenzoate (CAS 1340433-78-4)
- 2-(((6-Methoxypyridazin-3-yl)methyl)(methyl)amino)ethanol (CAS 1353961-06-4)
- Ethyl 2-{[(5E)-5-[(naphthalen-1-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}-6-oxo-1,6-dihydropyrimidine-5-carboxylate (CAS 866041-00-1)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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