Roflumilast Impurity 35 CAS CATO-C4X-108435
| CAS No. | CATO-C4X-108435 |
| Molecular Formula | C17H13Cl2F2N3O4 |
| Molecular Weight | 432.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Roflumilast Impurity 35 (CAS CATO-C4X-108435) is a certified pharmaceutical impurity reference standard with the molecular formula C17H13Cl2F2N3O4 and a molecular weight of 432.21 g/mol.
Based on its molecular formula C17H13Cl2F2N3O4, Roflumilast Impurity 35 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 432.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Roflumilast Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13Cl2F2N3O4 |
| Molecular Weight | 432.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Roflumilast Standards
- Roflumilast Impurity 54 (CAS CATO-C4X-108454)
- Roflumilast-D4 N-Oxide (CAS 1794760-31-8)
- Roflumilast N-Oxide (CAS 292135-78-5)
- Roflumilast Impurity 39 (CAS CATO-C4X-108439)
- Roflumilast USP Related Compound E (CAS 3031785-18-6)
- Roflumilast Impurity 6 (CAS 2368178-29-2)
- Roflumilast Impurity 3 (CAS 1391052-24-6)
- Roflumilast -D4 (CAS 1398065-69-4)
Recommended Standards
- Tethyl 4-(tributylstannyl)thiazole-2-carboxylate (CAS 173979-00-5)
- Lamotrigine-2N-glucuronide (CAS 135288-68-5)
- Methyl 5-(tributylstannyl)-2-thiazolecarboxylate (CAS 1447763-56-5)
- Lamotrigine 5 N Glucuronide (CAS 136565-77-0)
- Cetirizine Impurity 34 (CAS CATO-C4X-158234)
- N-Niroso Bilastine Impurity 77 (CAS CATO-C4X-225377)
- Rosiglitazone Impurity 3 (CAS 2142519-15-9)
- 3-[2-(4-methoxy-6-methyl-pyrimidin-5-yl)ethynyl]morpholine (CAS 2523120-31-0)
- 4-Bromo-3-(difluoromethyl)-5-(trifluoromethoxy)aniline (CAS 1805521-84-9)
- (S)-2-Acetamido-3-(2,3-difluoro-4-hydroxyphenyl)propanoic acid (CAS 1313277-87-0)
- Ethyl 3-(2-chloro-6-fluorophenyl)-2-(2-((3-chlorobenzyl)thio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)propanoate (CAS 477860-57-4)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(((tert-butoxycarbonyl)amino)methyl)phenyl)propanoic acid (CAS 1217729-44-6)
- Dyclonine Impurity 20 (CAS 35999-21-4)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com