Ambroxol Impurity 22 CAS CATO-C4X-108522
| CAS No. | CATO-C4X-108522 |
| Molecular Formula | C13H19BrN2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ambroxol Impurity 22 (CAS CATO-C4X-108522) is a certified pharmaceutical impurity reference standard with the molecular formula C13H19BrN2OHCl and a molecular weight of 335.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, Ambroxol Impurity 22 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Ambroxol Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H19BrN2O HCl |
| Molecular Weight | 335.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Impurity 28 (Ambroxol Monobromo) (CAS 101900-43-0)
- Ambroxol Impurity 33 HCl (CAS 101900-44-1)
- Ambroxol impurity 61 (CAS 104670-74-8)
- Ambroxol impurity 68 (CAS 105735-86-2)
- Ambroxol EP Impurity D (CAS 107814-37-9)
- Ambroxol D5DISCONTINUED, offer A575902 (CAS 1246818-80-3)
- Ambroxol impurity 113 (CAS 131417-90-8)
- Ambroxol impurity 116 (CAS 1373889-89-4)
Recommended Standards
- Letermovir impurity 110 (CAS CATO-C4X-2915110)
- Roflumilast impurity 23 (CAS 1369817-76-4)
- Dolutegravir Impurity 60 (CAS CATO-C4X-162060)
- 3-Cyano-4-fluorophenylboronic Acid (CAS 214210-21-6)
- Paclitaxel EP Impurity P (CAS 173101-56-9)
- 1-(4-Amino-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1356543-24-2)
- 2-(5-fluorothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1253586-81-0)
- (1R,2R,5R)-8-Azabicyclo[3.2.1]octane-2-carboxylic acid (CAS 71656-74-1)
- Ethyl 5-ethyl-4-fluoro-1H-pyrazole-3-carboxylate (CAS 681034-82-2)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com