Roflumilast impurity 23 CAS 1369817-76-4
| CAS No. | 1369817-76-4 |
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Roflumilast impurity 23 (CAS 1369817-76-4), a pharmacopoeial impurity reference standard (molecular formula C15H18O3, MW 246.30 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Roflumilast impurity 23 (C15H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Roflumilast impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
Related Roflumilast Standards
- Roflumilast Impurity 43 (CAS CATO-C4X-108443)
- Roflumilast Impurity 37 (CAS CATO-C4X-108437)
- Roflumilast impurity 17 (CAS 151103-09-2)
- Roflumilast impurity 21 (CAS 162401-78-7)
- Roflumilast Impurity 41 (CAS 1882067-43-7)
- Roflumilast Impurity C65 (CAS 162401-60-7)
- Roflumilast Impurity 10 (CAS 127842-54-0)
- Roflumilast Impurity 44 (CAS CATO-C4X-108444)
Recommended Standards
- (S)-N-Boc-phenylalaninenitrile (S)-tert-butyl 1-cyano-2-phenylethylcarbamate 99281-90-0 A11319 (CAS 99281-90-0)
- Escitalopram EP Impurity F (CAS 2102609-59-4)
- 41653-72-9 Lacinilene C 1,7-Dihydroxy-1,6-dimethyl-4-(1-methylethyl)-2(1H)-naphthalenone (CAS 41653-72-9)
- Citalopram Impurity 93 (CAS CATO-C4X-110993)
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- Halcinonide Impurity N2 (CAS 982-91-2)
- Moxifloxacin Impurity 42 (CAS CATO-C4X-107442)
- 1-(2-Fluorophenyl)-1h-imidazol-2-amine (CAS 1698842-02-2)
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- 6-Fluoro-3-methylbenzofuran-2-carbaldehyde (CAS 1186541-44-5)
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- Methyl 6-oxobicyclo[3.2.0]heptane-3-carboxylate (CAS 2137613-20-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com