Tadalafil Impurity 177 CAS CATO-C4X-1087177
| CAS No. | CATO-C4X-1087177 |
| Molecular Formula | C22H20N4O6 |
| Molecular Weight | 436.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tadalafil Impurity 177.
CATO supplies Tadalafil Impurity 177 (CAS CATO-C4X-1087177), a pharmacopoeial impurity reference standard (molecular formula C22H20N4O6, MW 436.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H20N4O6, Tadalafil Impurity 177 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 436.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tadalafil Impurity 177 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20N4O6 |
| Molecular Weight | 436.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Tadalafil Standards
- Tadalafil Impurity 157 (CAS CATO-C4X-1087157)
- Tadalafil Impurity 35 (CAS 2169996-11-4)
- Tadalafil Impurity 59 (CAS CATO-C4X-108759)
- Tadalafil Impurity 91 (CAS CATO-C4X-108791)
- Tadalafil Impurity 123 (CAS 2520114-73-0)
- Tadalafil Impurity 182 (CAS 2237219-65-5)
- Tadalafil Impurity 183 (CAS CATO-C4X-1087183)
- Tadalafil Impurity 158 (CAS 1863191-32-5)
Recommended Standards
- Apixaban Impurity 44 (CAS 536759-91-8)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-N,N-dimethyl-6-[(phenylsulfanyl)methyl]pyrimidin-4-amine (CAS 341965-55-7)
- N-Desmethyl N-Nitroso Topotecan (CAS CATO-C4X-17692)
- 2-((2,6-Dichlorobenzyl)thio)-N,N-dimethyl-6-((phenylthio)methyl)pyrimidin-4-amine (CAS 341965-38-6)
- Atrasentan Impurity 165 (CAS 1059043-32-1)
- Sapropterin Impurity 5 (CAS 17838-80-1)
- Nintedanib Impurity 98 (CAS 1860012-61-8)
- 5-Chloro-2-isopropoxy-pyridine-3-carbaldehyde (CAS 1289100-13-5)
- 5,5-Dimethyl-4-oxotetrahydrofuran-2-carboxylic acid (CAS 98272-75-4)
- Salmeterol Impurity 2 (CAS 160889-18-9)
- 3-(4-(Trifluoromethyl)phenyl)acrylonitrile (CAS 24654-53-3)
- 15N ammonium salt 15N labeled ammonium nitrate 31432-46-9 Ammonium nitrate-15N (CAS 31432-46-9)
- 15-Crown 5-Ether (CAS 33100-27-5)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com