Tadalafil Impurity 182 CAS 2237219-65-5
| CAS No. | 2237219-65-5 |
| Molecular Formula | C24H23N3O5 |
| Molecular Weight | 433.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tadalafil Impurity 182 (CAS 2237219-65-5), a pharmacopoeial impurity reference standard (molecular formula C24H23N3O5, MW 433.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tadalafil Impurity 182 (C24H23N3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 433.46 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tadalafil Impurity 182 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23N3O5 |
| Molecular Weight | 433.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related Tadalafil Standards
- Tadalafil Impurity 123 (CAS 2520114-73-0)
- Tadalafil Impurity 91 (CAS CATO-C4X-108791)
- Tadalafil Impurity 35 (CAS 2169996-11-4)
- Tadalafil Impurity 59 (CAS CATO-C4X-108759)
- Tadalafil Impurity 157 (CAS CATO-C4X-1087157)
- Tadalafil Impurity 177 (CAS CATO-C4X-1087177)
- Tadalafil Impurity 183 (CAS CATO-C4X-1087183)
- Tadalafil impurity 10 (CAS 629652-40-0)
Recommended Standards
- Linagliptin Impurity 41 (CAS 2074688-84-7)
- N-(4-Ethoxyphenyl)-2-imino-1-(2-methoxyethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 609797-34-4)
- N-Nitroso Ozanimod (CAS CATO-C4X-29023)
- N-(4-(Diphenylphosphoryl)phenyl)benzenesulfonamide (CAS 65089-13-6)
- Pemetrexed Impurity 59 HCl (CAS CATO-C4X-172659)
- Ruxolitinib Impurity N2 (CAS 191605-10-4)
- Sitafloxacin Isomer Impurity 8(RSS) (CAS CATO-C4X-11558)
- Oseltamivir Impurity 220 (CAS CATO-C4X-1720220)
- 5-[(3-bromophenyl)methyl]-4-methyl-1,3-thiazol-2-amine (CAS 1154374-43-2)
- (R)-1-(2-aminopyridin-3-yl)ethan-1-ol (CAS 936718-01-3)
- Ethyl 8-nitro-7-oxo-7,10-dihydro-1,10-phenanthroline-3-carboxylate (CAS 223664-49-1)
- 2-Bromo-5-(2-bromoethyl)furan (CAS 1341531-02-9)
- 2-(1,2-Benzoxazol-3-yl)-N-[(3-chlorophenyl)methyl]acetamide (CAS 860651-30-5)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com