Ezetimibe Impurity 117 CAS 1013025-04-1
| CAS No. | 1013025-04-1 |
| Molecular Formula | C25H24FNO5 |
| Molecular Weight | 437.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ezetimibe Impurity 117 (CAS 1013025-04-1), a pharmacopoeial impurity reference standard (molecular formula C25H24FNO5, MW 437.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ezetimibe Impurity 117 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 437.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ezetimibe Impurity 117 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H24FNO5 |
| Molecular Weight | 437.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 106 (CAS CATO-C4X-1098106)
- Ezetimibe Impurity 109 (CAS CATO-C4X-1098109)
- Ezetimibe Impurity 129 (CAS CATO-C4X-1098129)
- Ezetimibe Impurity 18 (CAS 204589-80-0)
- EzetimiBe Impurity 19 (CAS 1391053-63-6)
- Ezetimibe Impurity 88 (CAS 1618657-29-6)
- Ezetimibe Impurity 32 (CAS 1700622-08-7)
- Ezetimibe Impurity 142 (CAS CATO-C4X-1098142)
Recommended Standards
- Boc-Ala-Ala-Gly-pNA (CAS 90037-94-8)
- (2R,3S,4R,5R,6S)-5-(1,3-dioxoisoindolin-2-yl)-6-(ethylthio)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diyl diacetate (CAS 131545-00-1)
- Deucravacitinib Impurity 16 (CAS 2936652-48-9)
- Pitavastatin Impurity 116 (CAS CATO-C4X-1037116)
- Sitafloxacin Impurity 10 (CAS 185225-84-7)
- Efavirenz USP Related Compound C (CAS 391860-73-4)
- Difelikefalin Impurity 93 (CAS CATO-C4X-304193)
- Ethyl 7-bromo-1H-1,3-benzodiazole-5-carboxylate (CAS 1354771-56-4)
- 2-Methyl-N-((3-methyl-1h-pyrazol-4-yl)methyl)pentanamide (CAS 1178133-02-2)
- methyl 3-(((tert-butoxycarbonyl)amino)methyl)bicyclo[1.1.1]pentane-1-carboxylate (CAS 1638768-01-0)
- SM 16 (CAS 614749-78-9)
- (S)-1-(2-fluorophenyl)-2-methoxyethan-1-amine (CAS 1270288-22-6)
- 5-(2,3-Dimethylphenoxy)furan-2-carbaldehyde (CAS 1082167-93-8)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com