Apixaban Impurity 149 CAS CATO-C4X-1088149
| CAS No. | CATO-C4X-1088149 |
| Molecular Formula | C20H24BrN3O3 |
| Molecular Weight | 434.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apixaban Impurity 149 (C20H24BrN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Apixaban Impurity 149 (CAS CATO-C4X-1088149), a pharmacopoeial impurity reference standard (molecular formula C20H24BrN3O3, MW 434.33 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24BrN3O3 |
| Molecular Weight | 434.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Apixaban Standards
- Apixaban Impurity 181 (CAS CATO-C4X-1088181)
- Apixaban Impurity 133 (CAS CATO-C4X-1088133)
- Apixaban Impurity 44 (CAS 536759-91-8)
- Apixaban Impurity 58 (CAS CATO-C4X-108858)
- Apixaban Impurity 163 (CAS CATO-C4X-1088163)
- Apixaban Impurity 28 (CAS 503612-76-8)
- Apixaban Impurity 7 (CAS 1777781-49-3)
- Apixaban Impurity 57 (CAS CATO-C4X-108857)
Recommended Standards
- N'-[(1Z)-(4-Methylphenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 477864-08-7)
- RMC6236 Intermediate 13 (CAS 2641451-78-5)
- Ethyl 2,2-bis(4-(trifluoromethoxy)phenyl)cyclopropane-1-carboxylate (CAS 2563858-40-0)
- RMC6236 Intermediate 32 (CAS CATO-CIM-103920)
- Valaciclovir EP Impurity E (CAS 124832-31-1)
- Indocyanine green Impurity 59 (CAS CATO-C4X-250359)
- Butenafine Impurity N1 (CAS 79135-60-7)
- Bromfenac Impurity 6 (CAS 241496-82-2(free acid))
- tert-butyl N-(tert-butoxycarbonylamino)-N-[3-[4-(trifluoromethoxy)phenyl]-1-bicyclo[1.1.1]pentanyl]carbamate (CAS 2149634-58-0)
- 6-Methyl-1-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroquinoline (CAS 497059-98-0)
- 3-((2-Hydroxyphenyl)carbamoyl)-2,2-dimethylcyclopropane-1-carboxylic acid (CAS 1142214-40-1)
- n-(3-Hydroxypropyl)piperidine-4-carboxamide (CAS 91086-34-9)
- (3-((Methylamino)methyl)phenyl)boronic acid (CAS 1146614-39-2)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com