Apixaban Impurity 7 CAS 1777781-49-3
| CAS No. | 1777781-49-3 |
| Molecular Formula | C24H23N5O4 |
| Molecular Weight | 445.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Apixaban Impurity 7 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Apixaban Impurity 7 (CAS 1777781-49-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H23N5O4 and a molecular weight of 445.47 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Apixaban Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apixaban Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23N5O4 |
| Molecular Weight | 445.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 163 (CAS CATO-C4X-1088163)
- Apixaban Impurity 28 (CAS 503612-76-8)
- Apixaban Impurity 58 (CAS CATO-C4X-108858)
- Apixaban Impurity 44 (CAS 536759-91-8)
- Apixaban Impurity 133 (CAS CATO-C4X-1088133)
- Apixaban Impurity 181 (CAS CATO-C4X-1088181)
- Apixaban Impurity 149 (CAS CATO-C4X-1088149)
- Apixaban Impurity 27 (CAS 1074549-89-5)
Recommended Standards
- Azilsartan impurity 140 (CAS CATO-C4X-1096140)
- Entacapone Impurity 5（Mixture of chiral isomers） (CAS CATO-C4X-16295)
- N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-2,2-diphenylacetamide (CAS 95900-44-0)
- Baloxavir Marboxil Impurity 244 (CAS 2473028-59-8)
- Epinephrine Impurity 132 (CAS CATO-C4X-1849132)
- Perampanel Impurity 37 (CAS 61941-79-5)
- Zolpidem EP Impurity D (CAS 836627-56-6)
- 3-(1-Methyl-1H-pyrazol-5-yl)isoxazol-5-amine (CAS 1708436-27-4)
- 2-Amino-6-fluorophenylboronic Acid Pinacol Ester (CAS 1418130-40-1)
- trans-2-Hexen-1-yl Phenylacetate (CAS 68133-78-8)
- N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide (CAS 853314-72-4)
- Atorvastatin Impurity 52 (CAS 42558-54-3)
- 3-((4-Bromophenyl)(2,5-dimethylphenyl)methyl) -2,5-dimethylthiophene (CAS 1011800-93-3)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com