Alectinib Impurity 3 CAS 1256584-73-2
| CAS No. | 1256584-73-2 |
| Molecular Formula | C12H15IO2 |
| Molecular Weight | 318.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Alectinib Impurity 3 (CAS 1256584-73-2), a pharmacopoeial impurity reference standard (molecular formula C12H15IO2, MW 318.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, Alectinib Impurity 3 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alectinib Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15IO2 |
| Molecular Weight | 318.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
Related Alectinib Standards
- Alectinib Impurity 91 (CAS CATO-C4X-283691)
- Alectinib Impurity 67 (CAS CATO-C4X-283667)
- Alectinib impurity 01 (CAS 1256584-82-3)
- Alectinib impurity 27 (CAS CATO-C4X-283627)
- Alectinib Impurity 58 (CAS CATO-C4X-283658)
- Alectinib Impurity 48 (CAS CATO-C4X-283648)
- Alectinib Impurity 1 (CAS 1256578-99-0)
- Alectinib Impurity 65 (CAS CATO-C4X-283665)
Recommended Standards
- 2-{[(3,5-dichlorophenyl)amino]methylidene}-2,3-dihydro-1H-indene-1,3-dione 78872-37-4 MS-11212 (CAS 78872-37-4)
- tert-Butyl 4-iodo-3-methyl-benzoate (CAS 360059-33-2)
- 4,4,5,5-Tetramethyl-2-(3-((2,2,2-trifluoroethyl)thio)phenyl)-1,3,2-dioxaborolane (CAS 1026797-07-8)
- tert-Butyl 2-(4-iodophenyl)acetate (CAS 856250-87-8)
- Tirofiban Impurity 49 (CAS CATO-C4X-125449)
- Rotigotine Impurity 29 (CAS CATO-C4X-192729)
- Enzalutamide Impurity 63 (CAS 2997797-11-0)
- 2-(Pyrazolo[1,5-a]pyridin-3-yl)acetonitrile (CAS 118055-01-9)
- 2-(3-Formyl-5-(trifluoromethoxy)phenyl)acetonitrile (CAS 2167030-07-9)
- n-((1-((Tetrahydrofuran-3-yl)methyl)-1h-1,2,3-triazol-4-yl)methyl)cyclopropanamine (CAS 1495787-45-5)
- N,O-Didesmethyltramadol Hydrochloride (CAS 333338-16-2)
- 2-PYRIDIN-3-YL PIPERAZINE 3HCL (CAS 1171887-03-8)
- 2-Bromo-3-chlorobenzoyl chloride (CAS 116529-64-7)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com