Apixaban Impurity 95 CAS CATO-C4X-108895
| CAS No. | CATO-C4X-108895 |
| Molecular Formula | C22H20N4O5 |
| Molecular Weight | 420.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 420.42 g/mol gives Apixaban Impurity 95 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Apixaban Impurity 95 (CAS CATO-C4X-108895) is a certified pharmaceutical impurity reference standard with the molecular formula C22H20N4O5 and a molecular weight of 420.42 g/mol.
Apixaban Impurity 95 (C22H20N4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apixaban Impurity 95 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20N4O5 |
| Molecular Weight | 420.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 171 (CAS CATO-C4X-1088171)
- Apixaban Impurity 57 (CAS CATO-C4X-108857)
- Apixaban Impurity 73 (CAS CATO-C4X-108873)
- Apixaban Impurity 59 (CAS CATO-C4X-108859)
- Apixaban Impurity 177 (CAS CATO-C4X-1088177)
- Apixaban Impurity 183 (CAS CATO-C4X-1088183)
- Apixaban Impurity 185 (CAS CATO-C4X-1088185)
- Apixaban Impurity 149 (CAS CATO-C4X-1088149)
Recommended Standards
- CAS 2241669-86-1 (CAS 2241669-86-1)
- Azilsartan Impurity 124 (CAS CATO-C4X-1096124)
- Diethyl 2,2'-(butane-1,4-diylbis(azanediyl))bis(6-oxo-1,6-dihydropyrimidine-5-carboxylate) (CAS 92736-10-2)
- Azilsartan Impurity 133 (CAS CATO-C4X-1096133)
- Bendamustine Impurity 35 (CAS CATO-C4X-127135)
- Dolutegravir Impurity 24 (CAS 2315439-81-5)
- Brexpiprazole Impurity 1 (CAS 846038-18-4)
- 6-Bromo-1,2,3,4-tetrahydroisoquinoline Hydrochloride (CAS 215798-19-9)
- 2,5-Dimethyl-1-(3-methylbenzyl)-1H-pyrrole-3-carbaldehyde (CAS 937662-69-6)
- (S)-12-Hydroxy-3-oxo-N-(2-oxotetrahydrofuran-3-yl)dodecanamide (CAS 364749-97-3)
- 3-[2-Chloro-4-(1-methyl-1-phenylethyl)phenoxy]azetidine (CAS 1219960-83-4)
- PAPA NONOate (CAS 146672-58-4)
- 1-(2,2-Dibromoethenyl)cyclopropane (CAS 122244-78-4)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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