Apixaban Impurity 171 CAS CATO-C4X-1088171
| CAS No. | CATO-C4X-1088171 |
| Molecular Formula | C20H25ClN4O4 |
| Molecular Weight | 420.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apixaban Impurity 171 (C20H25ClN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Apixaban Impurity 171 (CAS CATO-C4X-1088171, C20H25ClN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apixaban Impurity 171 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H25ClN4O4 |
| Molecular Weight | 420.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 95 (CAS CATO-C4X-108895)
- Apixaban Impurity 57 (CAS CATO-C4X-108857)
- Apixaban Impurity 73 (CAS CATO-C4X-108873)
- Apixaban Impurity 59 (CAS CATO-C4X-108859)
- Apixaban Impurity 149 (CAS CATO-C4X-1088149)
- Apixaban Impurity 177 (CAS CATO-C4X-1088177)
- Apixaban Impurity 181 (CAS CATO-C4X-1088181)
- Apixaban Impurity 183 (CAS CATO-C4X-1088183)
Recommended Standards
- Levocetirizine Impurity 69 (CAS CATO-C4X-108369)
- Avanafil Impurity 11 (CAS 1638497-22-9)
- 2-Chloro-3-(4-(indoline-1-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 685106-73-4)
- Avanafil Impurity 123 (CAS CATO-C4X-1118123)
- Cinitapride Impurity 19 (CAS CATO-C4X-290819)
- Empagliflozin Impurity 82 (CAS 154006-52-7)
- Bambuterol impurity 13 (CAS 81732-65-2)
- 87592-77-6 C20H24O10 Smyrindioloside W1282 (CAS 87592-77-6)
- 5-Amino-1-ethyl-4-fluoropyridin-2(1H)-one (CAS 2757677-84-0)
- tert-Butyl 3-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate (CAS 2007916-87-0)
- Ethyl 3-bromo-2-(bromomethyl)-4,6-dimethoxybenzoate (CAS 105208-04-6)
- 1-Benzyl 1-tert-butyl cyclobutane-1,1-dicarboxylate (CAS 1624260-33-8)
- 1-Benzyl-4,4-bis(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1251923-79-1)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com