Rivaroxaban Impurity 126 DiHCl CAS CATO-C4X-1090126
| CAS No. | CATO-C4X-1090126 |
| Molecular Formula | C8H12N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Rivaroxaban Impurity 126 DiHCl (CAS CATO-C4X-1090126, C8H12N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rivaroxaban Impurity 126 DiHCl (C8H12N2OHCl) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 188.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O 2*HCl |
| Molecular Weight | 188.66 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Rivaroxaban Impurity 57 (CAS 1082495-22-4)
- Rivaroxaban Impurity 47 (CAS 1082588-73-5)
- Rivaroxaban-d4 (CAS 1132681-38-9)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
- Rivaroxaban EP Impurity I (CAS 1151893-81-0)
- Rivaroxaban 3-Hydroxy Metabolite (CAS 1159977-46-4)
- Rivaroxaban Impurity 15 (Mixture of Diastereomers) (CAS 1160169-99-2)
Recommended Standards
- Clindamycin Impurity 36(Mixture of Z and E Isomers) (CAS CATO-C4X-134136)
- Roxadustat Impurity 51 (CAS CATO-C4X-221351)
- Nicardipine Impurity 32 (CAS 134957-01-0)
- 5-Bromo-2-isopropoxypyridine (CAS 870521-31-6)
- 2-(Tricyclo[6.2.0.03,6]deca-1,3(6),7-trien-2-yl)acetic acid (CAS 2568008-64-8)
- Relugolix Impurity 171 (CAS CATO-C4X-2429171)
- 8-Methyl-1-thia-4-azaspiro[4.5]Decane (CAS 31404-03-2)
- 3,4-Dimethyl-5-hexen-3-ol (CAS 67760-91-2)
- 1-(4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)phenyl)ethan-1-one (CAS 338978-29-3)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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