Rivaroxaban Impurity 127 CAS CATO-C4X-1090127
| CAS No. | CATO-C4X-1090127 |
| Molecular Formula | C19H19ClN3O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Rivaroxaban Impurity 127 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Rivaroxaban Impurity 127 (CAS CATO-C4X-1090127) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19ClN3O4SCl and a molecular weight of 456.34 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Rivaroxaban Impurity 127 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 456.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H19ClN3O4S Cl |
| Molecular Weight | 456.34 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Rivaroxaban Impurity 57 (CAS 1082495-22-4)
- Rivaroxaban Impurity 47 (CAS 1082588-73-5)
- Rivaroxaban-d4 (CAS 1132681-38-9)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
- Rivaroxaban EP Impurity I (CAS 1151893-81-0)
- Rivaroxaban 3-Hydroxy Metabolite (CAS 1159977-46-4)
- Rivaroxaban Impurity 15 (Mixture of Diastereomers) (CAS 1160169-99-2)
Recommended Standards
- Glycopyrronium Bromide EP Impurity G (CAS 13118-11-1)
- Risperidone Impurity 25 (CAS 832747-59-8)
- 【禁售不询】Tadalafil Impurity 43 (CAS 120-57-0)
- 1-(2-(Benzyloxy)-5-bromophenyl)adamantane (CAS 736992-49-7)
- 3-(1H-Imidazol-5-yl)-N-isopropylacrylamide (CAS 952733-22-1)
- 2-(6-Bromo-5-(bromomethyl)-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805950-23-5)
- Des-Arg Cetrorelix Acetate (CAS CATO-C4X-20148)
- 2-(2,4-Dimethyl-phenylamino)-N-(4-methyl-thiazol-2-yl)-propionamide (CAS 1008918-60-2)
- 1-(3-Hydroxyphenyl)ethyl 1H-pyrrole-2-carboxylate (CAS 65171-92-8)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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